Results 51 to 60 of about 168,759,165 (271)

Assessment of the Myasthenia Gravis Patients’ Quality of Life

Pielęgniarstwo Neurologiczne i Neurochirurgiczne, 2023
Introduction. Myasthenia gravis is an immune-mediated disease associated with a disorder of the neuromuscular junction. MG belongs to the group of chronic diseases with variable clinical courses.
Weronika Jung-Plath, Marcelina Skrzypek-Czerko, Małgorzata Bilińska, Agata Zdun-Ryżewska   +3 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The Relationship Between Mental State and Functional Status in Elderly Residents of Kahrizak

Sālmand, 2010
Objectives: The current study was performed to investigate the relationship between mental impairment and each component of activity of daily living (ADL) in elderly residents of the Kahrizak Charity Foundation. Methods & Materials: Standardized Iranian
Hadi Kazemi, Sima Ghasemi, Farshad Sharifi, Hossein Fakhrzadeh, Maryam Ghaderpanahi, Mojde Mirarefin, Mahshid Foroughan, parvaneh Mohammadkhani   +7 more
doaj  

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Association between chronic disease comorbidity patterns and activities of daily living among permanent elderly residents in Xuhui District of Shanghai

Shanghai yufang yixue
ObjectiveTo investigate the patterns of chronic disease comorbidity among permanent elderly residents in Xuhui District of Shanghai, and to analyze the impact of different comorbidity patterns on the elderly’s ability to perform activities of daily ...
XU Qian, ZHANG Xiaohong, QIAN Xiaolin, ZHU Jing, CHEN Yun, YAN Fei, FU Chaowei, GU Haiyan   +7 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Gaussian process modelling of blood glucose response to free-living physical activity data in people with type 1 diabetes

, 2009
Good blood glucose control is important to people with type 1 diabetes to prevent diabetes-related complications. Too much blood glucose (hyperglycaemia) causes long-term micro-vascular complications, while a severe drop in blood glucose (hypoglycaemia ...
Chipperfield, Andrew J., Valletta, John Joseph, J.J. Valletta, A.J. Chipperfield, Byrne, Christopher D., C.D. Byrne   +5 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Value of the Barthel scale in prognostic prediction for patients with cerebral infarction

BMC Cardiovascular Disorders, 2020
Background This study aims to evaluate the ADL(activity of daily living) of patients with acute cerebral infarction through BI scoring, in order to observe its predictive value in the prognosis of these patients.
Qun-Xi Li, Xiao-Jing Zhao, Yan Wang, Da-Li Wang, Jiang Zhang, Tie-Jun Liu, Yan-Bo Peng, Hai-Yan Fan, Fu-Xia Zheng   +8 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source