Results 101 to 110 of about 980,735 (314)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Recognition of Sedentary Behavior by Machine Learning Analysis of Wearable Sensors during Activities of Daily Living for Telemedical Assessment of Cardiovascular Risk

open access: yesSensors, 2018
With the recent advancement in wearable computing, sensor technologies, and data processing approaches, it is possible to develop smart clothing that integrates sensors into garments.
Eliasz Kańtoch
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Towards Human Activity Recognition: A Hierarchical Feature Selection Framework

open access: yesSensors, 2018
The inherent complexity of human physical activities makes it difficult to accurately recognize activities with wearable sensors. To this end, this paper proposes a hierarchical activity recognition framework and two different feature selection methods ...
Aiguo Wang   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

ShoeTect2.0: Real-Time Activity Recognition Using MobileNet CNN with Multisensory Smart Footwear

open access: yes
260268In this paper, we introduce a proof-of-concept multi-sensory footwear prototype with artificial intelligence to facilitate human activity recognition.
Matthies, Denys   +3 more
core   +1 more source

Activity recognition using Grey-Markov model [PDF]

open access: yes, 2011
Activity Recognition (AR) is a process of identifying actions and goals of one or more agents of interest. AR techniques have been applied to both large and small scale activity identification.
NC DOCKS at Western Carolina University   +1 more
core  

2nd International Workshop on Sensor-based Activity Recognition and Interaction, iWOAR 2015. Proceedings

open access: yes, 2022
Wearable sensors potentially enable for a better and unobtrusive recognition of human activity and the state of rest, sleep, stress and drive the ongoing trend of the quantified self-movement.

core  

Deep neural network based human activity recognition for the order picking process

open access: yes, 2022
Art. 14, 6 S.Although the fourth industrial revolution is already in progress and advances have been made in automating factories, completely automated facilities are still far in the future.
Fink, Gernot A.   +5 more
core   +1 more source

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