Results 121 to 130 of about 3,944,530 (288)

Activity theory as a framework for teaching mathematics: An experimental study. [PDF]

Heliyon, 2022
Loc NP, Oanh NPP, Thao NP, De TV, Triet LVM.   +4 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Comment: Thinking About Open Access—Concretely

Forum: Qualitative Social Research, 2006
In a recent review essay concerning open access (VALSINER, 2006), readers are confronted with some claims about the shifting of publication costs from the producer to the user without actually facilitating access to the products of scientific research ...
Wolff-Michael Roth
doaj  

Experiences of Online and In-Person Learning: A Case Study of Doctoral Education

Social Sciences
Teaching in a globalised world offers opportunities to reduce barriers, enhance understanding, and expand access for diverse learners. Blended approaches, combining in-person and online delivery, can encourage learning communities across geographical ...
Alan Marvell, Louise Livesey
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Developing Learning Technology Professionals in the Scholarship of Teaching and Learning (SoTL): Insights from a Cross-Institutional Mentor Scholar Scheme

Trends in Higher Education
Debates are taking place in the higher education literature regarding the changing roles of learning technology professionals and their contributions to the scholarship of teaching and learning (SoTL).
Denise Sweeney, Jessica Humphreys, Tünde Varga-Atkins, Brett Bligh, Jim Turner   +4 more
doaj   +1 more source

Current research trends on cognition, integrative complexity, and decision-making: a systematic literature review using activity theory and neuroscience. [PDF]

Front Psychol, 2023
Molina I, Molina-Perez E, Sobrino F, Tellez-Rojas MA, Zamora-Maldonado HC, Plaza-Ferreira M, Orozco Y, Espinoza-Juarez V, Serra-Barragán L, De Unanue A.   +9 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Balancing innovation and mentorship in postgraduate supervision through activity theory and artificial intelligence

Educational Technology Quarterly
This study presents a systematic literature review that maps the emerging role of Artificial Intelligence (AI) in postgraduate research supervision.
Gardner Mwansa, Matipa Ricky Ngandu, Mushimbei Mwilima Mwansa   +2 more
doaj   +1 more source

Using cultural historical activity theory to reflect on the sociocultural complexities in OSCE examiners' judgements. [PDF]

Adv Health Sci Educ Theory Pract, 2023
Wong WYA, Thistlethwaite J, Moni K, Roberts C.   +3 more
europepmc   +1 more source