Results 131 to 140 of about 603,389 (218)

Chinese calligraphy as cultural mediation: a cultural-historical activity theory perspective on therapeutic practice for neuropsychiatric symptoms. [PDF]

Front Psychiatry
Chu KY.
europepmc   +1 more source

Understanding EFL Teacher Engagement in TDTs' Collaborative Curriculum Design: A Chinese Case Study From the Activity Theory Perspective. [PDF]

Front Psychol, 2022
Wu Z, Li J, Cheng L.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Examining older adults' vulnerability to online health scams: insights from routine activity theory. [PDF]

Front Public Health
Chen H, He M, Xu X, Atkin D.
europepmc   +1 more source

Cultural Historical Activity Theory for Studying Practice-Based Learning and Change in Medical Education. [PDF]

Adv Med Educ Pract, 2021
Qureshi SP.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

An activity theory-based exploration of "Eyeland", a task-based serious game for EFL visually impaired students. [PDF]

PeerJ Comput Sci
Villalba K, Robles H, Jimeno M, Delgado-Cañas MC, Perez A, Quintero F.   +5 more
europepmc   +1 more source

Vietnamese non-English-major students' motivation to learn English: from activity theory perspective. [PDF]

Heliyon, 2021
Nguyen SV, Habók A.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

From Learner to Provider: Navigating Role Tensions in Postgraduate Medical Training Through Activity Theory. [PDF]

Perspect Med Educ
Kwong SP, Yu SR, Liao KC, Liao SC, Hsiao CT, Chaou CH.   +5 more
europepmc   +1 more source