Results 21 to 30 of about 11,031 (215)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Live Online Education Efficiency Mediators From the Actor Network Theory Perspective
Frontiers in Education, 2022 PurposeThe purpose of this research was to explore the conceptual network of live online education efficiency from the Actor Network Theory perspective to reveal different aspects influencing the quality of online training less accounted for in previous ...
Radoslaw Czahajda +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Nordic Journal of Science and Technology Studies, 2014 This special issue of the Nordic Journal of Science and Technology Studies is interested in how nature, in different versions and forms, is invited into our studies, analyses, and stories. How is it that we “write nature”? How is it that we provide space
Kristin Asdal, Gro Birgit Ween
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Computerization of primary health care in Brazil: the network of actors
Revista Brasileira de Enfermagem, 2019 Objective: To analyze the network of human and non-human actors involved in the computerization of primary health care in the Brazilian federal government.
Ricardo Bezerra Cavalcante +5 more
doaj +1 more source
Georg Brandes as an Actor Narrating a Story about Poland
Acta Universitatis Carolinae Philologica, 2023 The aim of the article is to investigate Brandes’s impact on the Poles’ self-image and to explain how he became an actor in an internal Polish network of relationships. Three aspects have been analysed with regard to this aim: the reception of Brandes in
Sylwia Izabela Schab
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A midrange theory of local cross-sector action based on the actor-network theory
SSM: Qualitative Research in Health, 2022 Given the value of cross-sector collaborations in solving complex societal problems, experts are now recommending that research focus on documenting process–effect linkages.
Angèle Bilodeau +5 more
doaj +1 more source