Results 111 to 120 of about 359,514 (275)

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Actor-networks and the diffusion of management accounting innovations : a comparative study. [PDF]

open access: yes
This research is concerned with the diffusion of management accounting innovations viewed as a process of actor-network building and translation. The aim is to better understand the nature of accounting change.
Alcouffe, Simon   +2 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Opening the black box of commodification: A philosophical critique of actor-network theory as critique [PDF]

open access: yes
This article argues that actor-network theory, as an alternative to critical theory, has lost its critical impetus when examining commodification in healthcare.
Hvid, Henrik Rude
core  

Hydrogen's potential and policy pathways for Indonesia's energy transition: The actor-network analysis

open access: yesUnconventional Resources
This research examines potential uses of hydrogen as an alternative energy source in Indonesia. Hydrogen presents a more environmentally friendly energy alternative with markedly reduced greenhouse gas emissions, leading the Indonesian government to ...
Chrisna T. Permana   +2 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

The Matter of Entrepreneurial Learning: A Literature Review [PDF]

open access: yes, 2010
This paper is a comprehensive review of the entrepreneurial learning literature and its engagement with the material aspects of entrepreneurship, as part of the “material turn” in the social sciences.
Erdelyi, Peter
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Nowe technologie i kryzys demokracji liberalnej w perspektywie teorii aktora-sieci

open access: yesPoliteja
NEW TECHNOLOGIES AND THE CRISIS OF LIBERAL DEMOCRACY FROM THE PERSPECTIVE OF ACTOR-NETWORK THEORY There are two different perspectives in political science regarding the assessment of the impact of technology.
Arkadiusz Lewandowski   +1 more
doaj   +1 more source

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