Results 111 to 120 of about 1,955,465 (354)

Addressing Function Approximation Error in Actor-Critic Methods [PDF]

open access: yes, 2018
In value-based reinforcement learning methods such as deep Q-learning, function approximation errors are known to lead to overestimated value estimates and suboptimal policies.
Fujimoto, Scott   +2 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Le merveilleux psychique en spectacle : artistes somnambules et divas italiennes

open access: yesItinéraires
Between the end of the 19th and the beginning of the 20th century, “unconscious artists” multiplied on European stages, accompanied by their “operators” (psychologists, doctors, scholars). In a state of trance, women with nervous sensitivity were capable
Mireille Berton
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of actor-networks in the diffusion of management accounting innovations: a comparative study of budgetary control, GP method and Activity-Based Costing in France [PDF]

open access: yes
This research is concerned with the diffusion of management accounting innovations viewed as a process of actor-network building and translation. The aim is to better understand the nature of accounting change.
Nicolas Berland   +2 more
core  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The Impact of an Epic Theater in The Kurdish Theater Bertold Brecht as an Example

open access: yesمجلة جامعة كويه للعلوم الانسانية والاجتماعية, 2019
This research studies the theories of fiction theater by the famous German writer and director Bertolt Brecht. He could develop it as a type of drama theater, and it has become an independent school in the field worldwide. Also, many other directors have
Kaify A. Abdulqader, Zhilwan T. Bapir
doaj   +1 more source

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