ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Requirements and Use Cases for eHealth Solutions in Flexible Assertive Community Treatment Teams: Design Science Study. [PDF]
Bønes E, Granja C, Solvoll T.
europepmc +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
First Evidences of the Point-Light Display Observation Methodology in Multi-Pathology Care: A Retrospective Analysis. [PDF]
Francisco V +5 more
europepmc +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Comparing Patient Simulation With a Humanoid Robot or a Human Actor in Terms of Training Success and Acceptance: Pilot Questionnaire Study. [PDF]
Schwarz P +5 more
europepmc +1 more source
Spatio-Temporal Dynamics and Diversity of Approaches in Multiscale Fire Governance. [PDF]
Neger C +3 more
europepmc +1 more source
Effectiveness of Smartphone-Based Dyadic Interventions to Increase Physical Activity in Romantic Couples: Microrandomized Trial. [PDF]
Höhener PS +4 more
europepmc +1 more source
The family, school and community linkage of improving adolescent physical fitness and health: based on the ANT. [PDF]
Liu Y, Zhu Q, Li S, Yao L, Wang D.
europepmc +1 more source
Sociodemographic and medical correlates of fertility-related quality of life in primary infertile Czech couples attending fertility clinics. [PDF]
Kučerová JD +6 more
europepmc +1 more source

