Results 71 to 80 of about 1,341,927 (270)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Behavioural Types for Actor Systems

open access: yes, 2012
Recent mainstream programming languages such as Erlang or Scala have renewed the interest on the Actor model of concurrency. However, the literature on the static analysis of actor systems is still lacking of mature formal methods.
Crafa, Silvia
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Harvesting living labs outcomes through learning pathways

open access: yesCurrent Research in Environmental Sustainability
Living labs have emerged as a long-term, collaborative approach to addressing complex societal challenges, such as sustainable land and water management and climate change adaption.
Astha Bhatta   +2 more
doaj   +1 more source

The changing nature of urban public places in Dhaka City [PDF]

open access: yesUrbanism. Arhitectura. Constructii, 2014
Throughout the history, public places have been asserted as one of the key components of urban life for their physical, social, political, symbolic and environmental roles.
Mashrur Rahman Mishu   +2 more
doaj  

Ontology-Mediated Historical Data Modeling: Theoretical and Practical Tools for an Integrated Construction of the Past

open access: yesInformation, 2020
Building upon the concepts of constructed past theory, this paper introduces the outcome of ontology-mediated data modeling developed by the authors within the last 15 years.
Esther Travé Allepuz   +2 more
doaj   +1 more source

Predicting Multi-actor collaborations using Hypergraphs [PDF]

open access: yes, 2014
Social networks are now ubiquitous and most of them contain interactions involving multiple actors (groups) like author collaborations, teams or emails in an organizations, etc.
Chandra, Abhishek   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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