Results 91 to 100 of about 23,077 (281)
Intersectoral Collaboration to Promote Child Development: The Contributions of the Actor-Network Theory. [PDF]
Qual Health Res, 2023 Chiari APG +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Machines and machinations: The integrated care record service in the UK national health service
, 2005 This paper examines the use of Actor Network Theory (ANT) as a lens to get a better understanding of the implementation of the Integrated Care Record Service (ICRS) in the UK National Health Service (NHS).
Christopher Atkinson +11 more
core +1 more source
The gender of science: reflections on the actor-network theory and the feminist perspective
Mediações: Revista de Ciências Sociais, 2015 This article discusses some of the principles that guide the descriptive forms of the actor-network theory (ANT) of Bruno Latour and feminist standpoint theory formulated by Sandra Harding and Evelyn Fox Keller, through my research on the "Marie Curie ...
Gabriel Pugliese Cardoso
doaj +1 more source
Black boxes and information pathways: An actor-network theory approach to breast cancer survivorship care. [PDF]
Soc Sci Med, 2022 Lefkowitz D.
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Revisiting agency and medical health technology: actor network theory and breast cancer survivors' perspectives on an adherence tool. [PDF]
Health Technol (Berl), 2022 Cabling ML +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
An Actor-Network Theory of Cosmopolitanism
, 2011 A major problem with the emerging sociological literature on cosmopolitanism is that it has not adequately theorized mechanisms that mediate the presumed causal relationship between globalization and the development of cosmopolitan orientations. To solve
SAITO, Hiro, Hiro Saito
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source