Results 71 to 80 of about 23,077 (281)
Using actor-network theory to reveal strategy processes in design firms [PDF]
, 2017 In this paper we illustrate the utility of actor-network theory (ANT) as a methodological approach to understand the effect of the eclectic characteristics of design firms on their strategy development processes.
Rieple, A., van den Broek, A.
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, 2003 Many older people are discovering the Internet, and some are also making good use of electronic commerce and all that goes with it. Others, however, are not adopting these technologies.
Tatnall, Arthur, Lepa, Jerzy
core +1 more source
Market devices and structural dependency: The origins and development of ‘dark pools’
Finance and Society, 2019 ‘Dark pools’ are private, electronic share-trading systems in which participants cannot see each other's buy and sell orders. This article shows that the development of these material ‘market devices’ was strongly shaped by the structural dependency of ...
Donald MacKenzie
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
The use of Actor-Network Theory and a Practice-Based Approach to understand online community participation [PDF]
, 2013 Participation in online communities is problematic. Take up of community technologies is often patchy and subject to resistance, particularly in organisational settings.
Rivera, Gibran
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Revista de Filosofia, 2016 In this paper are discussed the contributions of the contemporary sociological theory to the philosophical and scientical question of Ontology, for this purpose are compared the ontological assumptions elaborated for the General Social Systems Theory by ...
Sergio Pignuoli Ocampo
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Combining Luhmann and Actor-Network Theory to see Farm Enterprises as Self-organizing Systems
, 2006 From a rural, sociological point of view no social theories have so far been able to grasp the ontological complexity and special character of a farm enterprise as an entity in a really satisfying way.
Noe, Egon, Alrøe, Hugo Fjelsted
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