Results 101 to 110 of about 359,749 (276)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

American Long-Distance Locomobility and the Spaces of Actor-Network Theory

Social Sciences, 2016
Much of the discourse surrounding national intercity passenger rail service in the United States revolves around why it has lagged so far behind European and Asian counterparts.
Michael Minn
doaj   +1 more source

Intersectoral Collaboration to Promote Child Development: The Contributions of the Actor-Network Theory. [PDF]

Qual Health Res, 2023
Chiari APG, Senna MIB, Gomes VE, Freire MDSM, Soares ARDS, Alves CRL, Cury GC, Ferreira RC.   +7 more
europepmc   +1 more source

Resources of actor-network theory for daily mobility researches [PDF]

, 2015
Resources of actor-network theory for daily mobility researches are examined. Reconstruction of social space term from ANT point of view allows understanding daily mobility as a phenomenon providing reproduction of social links.В работе рассматриваются ...
Danilova, A., Данилова, А. В.
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Black boxes and information pathways: An actor-network theory approach to breast cancer survivorship care. [PDF]

Soc Sci Med, 2022
Lefkowitz D.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Revisiting agency and medical health technology: actor network theory and breast cancer survivors' perspectives on an adherence tool. [PDF]

Health Technol (Berl), 2022
Cabling ML, Drago F, Turner J, Hurtado-de-Mendoza A, Sheppard VB.   +4 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Hydrogen's potential and policy pathways for Indonesia's energy transition: The actor-network analysis

Unconventional Resources
This research examines potential uses of hydrogen as an alternative energy source in Indonesia. Hydrogen presents a more environmentally friendly energy alternative with markedly reduced greenhouse gas emissions, leading the Indonesian government to ...
Chrisna T. Permana, Chanel Tri Handoko, Konstantin Gomonov   +2 more
doaj   +1 more source