Results 111 to 120 of about 1,968,307 (261)

Emerging Non-state Actors in Global Development: Challenges for Europe [PDF]

open access: yes, 2010
As part of the broader research programme on how 'new actors in international development' might influence European development cooperation in the coming decade, this paper provides an overview of the engagement of three types of non-state development ...
Erik Lundsgaarde
core  

An actor manages: actor training and managerial ideology

open access: yesTheatre, Dance and Performance Training, 2014
This article reads the development of psychologically based actor training against larger changes in the organisation of work in North America and Europe in the twentieth century. Konstantin Stanislavky's System and later adaptations including the American Method are wrapped into a larger ideology of individual self-management and discipline – mental ...
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Territorial resources and tourist destinations: couples with a bright future?

open access: yesRevue de Géographie Alpine, 2014
Cultural tourism is based on the construction of destinations with attributes that are recognized and prized by people outside the area. A destination is an ensemble of territory-specific resources whose uniqueness is highlighted by their anchorage ...
Pierre-Antoine Landel   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Strengthening Collaboration among Philanthropy Actors in the Education Sector [PDF]

open access: yes, 2015
The Kenya Philanthropy Forum (KPF) is a platform that seeks to strengthen coordination among philanthropy actors and other stakeholders; promote an enabling environment for philanthropy and heighten the recognition of the philanthropy sector in the ...

core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Stochastic Evolutionary Growth Model for Social Networks

open access: yes, 2006
We present a stochastic model for a social network, where new actors may join the network, existing actors may become inactive and, at a later stage, reactivate themselves.
Fenner, Trevor   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Inside the Womb: Interpreting the Ferguson Case [PDF]

open access: yes, 2002
The rise of globalization has made ​​the sustainability aspect emerged as a sign that peoples’ actions must change. Tourism is now one of the fastest growing industries in the world that has an impact on people, nature and cultures.
Werauch, Samantha
core   +1 more source

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