Results 201 to 210 of about 1,968,307 (261)
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
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Journal relatedness: An actor-actor and actor-objectives case study
Scientometrics, 2007Using the MACTOR (Matrix of Alliances and Conflicts: Tactics, Objectives and Recommendations) method, a set of 13 related journals covering the subject category “Chemistry, Multidisciplinary” was analyzed in terms of direct and indirect reciprocal influences (measured by relatedness indexes Rji), their positions towards a generic set of common ...
Radu Munteanu, Marin Apetroae
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Actor classification using actor machines
2013 Asilomar Conference on Signals, Systems and Computers, 2013Program analysis is an important tool in software development, both for verifying desired properties and for enabling optimizations. For dataflow programs, properties such as determinacy and static schedulability are important for verifying correctness and creating efficient implementations. In this paper we develop an analyzer for dataflow actors, the
Gustav Cedersjo, Jörn W. Janneck
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Knowledge based actor to actor coordination in Wireless Sensor and Actor Networks
ETFA2011, 2011Wireless Sensor and Actor Networks emphasize the necessity for cooperative communication between actors as well as sensors in order to achieve ubiquitous monitoring and efficient interaction in realistic physical environments and appropriate acting on them.
Sofia-Maria Dima +2 more
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2019 Forum for Specification and Design Languages (FDL), 2019
Actors have become widespread in programming languages and programming frameworks focused on parallel and distributed computing. While actors provide a more disciplined model for concurrency than threads, their interactions, if not constrained, admit nondeterminism. As a consequence, actor programs may exhibit unintended behaviors and are less amenable
Marten Lohstroh, Edward A. Lee
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Actors have become widespread in programming languages and programming frameworks focused on parallel and distributed computing. While actors provide a more disciplined model for concurrency than threads, their interactions, if not constrained, admit nondeterminism. As a consequence, actor programs may exhibit unintended behaviors and are less amenable
Marten Lohstroh, Edward A. Lee
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Formal Aspects of Computing, 2003
Abstract.Modern environments for modelling and designing concurrent computational systems increasingly supportheterogeneoussystem models, which are characterised by different coordination mechanisms governing the interaction between concurrent components in different parts or at different levels of the model.
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Abstract.Modern environments for modelling and designing concurrent computational systems increasingly supportheterogeneoussystem models, which are characterised by different coordination mechanisms governing the interaction between concurrent components in different parts or at different levels of the model.
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IEEE Concurrency, 1998
The terms "actor" and "agent" are used widely in the literature on concurrent and distributed programming both because the underlying concepts to which they refer are fundamental, powerful, and interesting and also because these terms admit of varying interpretations in different technical settings. Historically, the terms "actor" and "agent" have
Dennis G. Kafura, Jean-Pierre Briot
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The terms "actor" and "agent" are used widely in the literature on concurrent and distributed programming both because the underlying concepts to which they refer are fundamental, powerful, and interesting and also because these terms admit of varying interpretations in different technical settings. Historically, the terms "actor" and "agent" have
Dennis G. Kafura, Jean-Pierre Briot
openaire +1 more source

