Results 71 to 80 of about 862,257 (255)

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park   +5 more
wiley   +1 more source

ADAPTATION OF THE EDUCATIONAL PROGRAM FOR FINANCIAL CALCULATIONS ACCORDING TO THE ACTUAL ECONOMIC STATE

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2017
This paper presents an innovative approach to teaching the discipline ‘Financial calculations‘, which based on a dynamic block of case studies generated by information received online from the stock market.
Ekaterina P. Mochalina   +3 more
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Methods of analysis of gut microorganism – actual state of knowledge

open access: yesAnnals of Agricultural and Environmental Medicine, 2014
[b]introduction[/b]. Microbiota plays an integral part in maintaining organism homeostasis, through eliminat pathogens, anti-cancer activity, synthesis of digestive enzymes and vitamins, maintaining the continuity of the intestinal epithelium and ...
Iwona Ignyś   +4 more
doaj  

ASSESSMENT OF THE ACTUAL NUTRITIONAL STATE OF PREGNANT AND LACTATING WOMEN

open access: yesМать и дитя в Кузбассе, 2020
The aim of our study is to assess the actual implementation of the recommendations on the nutrition of pregnant and lactating women from both the medical staff and the women themselves. The study included 5753 women, of whom 5.6 % were pregnant and 94.4 %
Яков Яковлевич Яковлев   +4 more
doaj  

History and Actual State of Non-HEU Fission-Based Mo-99 Production with Low-Performance Research Reactors

open access: yesScience and Technology of Nuclear Installations, 2013
Fifty years ago, one of the worldwide first industrial production processes to produce fission-Mo-99 for medical use had been started at ZfK Rossendorf (now: HZDR, Germany).
S. Dittrich
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

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