Results 61 to 70 of about 37,741 (290)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket   +14 more
wiley   +1 more source

Aristotle and Heidegger: Potentiality in Excess of Actuality

open access: yes, 2016
Aristotle claims in book 9 of the Metaphysics that potentiality is distinct from actuality yet also that potentiality exists only for the sake of actuality. This essay presents the relationship between potentiality’s existence and actuality’s priority as
Brown, Nahum Carl HUMA
core   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

The alleged activity of active intellect: A wild goose chase or a puzzle to be solved?

open access: yesZagadnienia Filozoficzne w Nauce, 2014
Trying to describe the activity of Aristotle’s active intellect, we will sooner or later realize that we cannot find its right description, because Aristotle did not provide for one.
Sonia Kamińska
doaj  

Actualism, Serious Actualism, and Quantified Modal Logic

open access: yesNotre Dame Journal of Formal Logic, 2018
The paper navigates in the waters between metaphysical doctrine and formal logical representation. The goal is to build a first-order modal logic that accommodates both ``actualism'' (the view there are no merely possible things, that is, things that do not exist but have some alternative kind of being) and ``serious actualism'' (that all sentences ...
openaire   +2 more sources

The Course of Actualization [PDF]

open access: yesLanguage, 2012
Actualization is traditionally seen as the process following syntactic reanalysis whereby an item’s new syntactic status manifests itself in new syntactic behavior. The process is gradual in that some new uses of the reanalyzed item appear earlier or more readily than others.
openaire   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

On the Actuality of Forms

open access: yesMateria Arquitectura, 2014
The essay discusses some of the techniques Josef Albers, the famous artist-educator, employed in his own work and in his teaching to make form activate the mind of the creator.
Eeva-Liisa Pelkonen
doaj   +1 more source

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