Results 41 to 50 of about 30,157 (315)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Predictors of Self-Actualization
, 2016 The Theory on Attaining Self-actualization among Older Adults stated that there are characteristics that a person should develop which will enable him or her to become self-actualized.
Pausanos, Melinda
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Вестник Северо-Кавказского федерального университетаIntroduction. Modernization of teacher education involves the search for new solutions to improve the quality of training of teachers and assess the quality of their professional training.
A. I. Mezentseva
doaj +1 more source
Модели, системы, сети в экономике, технике, природе и обществе, 2022 Background. The penetration of information technologies into all spheres of life, the introduction of distance education methods, open access to information and educational resources has led to the need to introduce and develop a model of convergent ...
M.V. Deev +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
An epistemological critique of self-actualization psychology
, 2020 In view of an ostensible renaissance of the self-actualization concept, it seems appropriate to question what exactly self-actualization is. In psychology, Abraham Maslow introduced self-actualization in his motivation theory, taken up by other ...
Roose, Daniel
core +1 more source
Career decision making, stability and actualization of career intentions: The case of entrepreneurial intentions [PDF]
, 2013 Career counselors are often concerned with stability and likelihood of implementation of clients’ career intentions. It is often assumed that the status in career decision making (CDM) is one likely indicator, yet empirical support for this assumption is
Hirschi, A., Hirschi, Andreas
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Les Enfants de Poucet : Avatars du conte dans le théâtre francophone contemporain (1989-2012)
ILCEA, 2014 For the past twenty years, one of the best-known traditional French tales known as “Le Petit Poucet” (Little Thumbling) by Charles Perrault has been more and more present in the art world.
Martial Poirson
doaj +1 more source