Results 51 to 60 of about 39,612 (265)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Armenian Folia Anglistika, 2016 The article aims at disclosing the concept God in J. Fowles philosophical essay “The Aristos” as well as defining linguistic means of its actualization.
Heghine Isahakyan
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Les interprétations sémantiques des groupes nominaux sans déterminant en ancien-haut-allemand
Corela, 2023 In modern German, singular noun phrases without any actualizer (type [ØN]sg) encode a non-discrete and undefined aim. In old high German, the marking of nominal categories is the object of current development, and the interpretation of a noun phrase ...
Delphine Pasques
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Career decision making, stability and actualization of career intentions: The case of entrepreneurial intentions [PDF]
, 2013 Career counselors are often concerned with stability and likelihood of implementation of clients’ career intentions. It is often assumed that the status in career decision making (CDM) is one likely indicator, yet empirical support for this assumption is
Hirschi, A., Hirschi, Andreas
core +2 more sources
Fonction de l’article vis-à-vis de l’absence d’article : focalisation plutôt qu’actualisation ?
Corela, 2023 The general function of the determinant is usually described by linguists and grammarians in terms of “actualization”, referring explicitly or implicitly to the passage of a sign from a “potential” to an “effective” status.
Lidia Lebas-Fraczak
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Consentability, Autonomy, and Self-Actualization [PDF]
, 2020 This essay evaluates several competing principles underlying consent, such as self-interest, self-sovereignty, and self-actualization. Witmer-Rich argues that the nature of consent depends heavily on which of these underlying values consent is believed ...
Witmer-Rich, Jonathan
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source