Results 51 to 60 of about 147,627 (276)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Les Enfants de Poucet : Avatars du conte dans le théâtre francophone contemporain (1989-2012)
ILCEA, 2014 For the past twenty years, one of the best-known traditional French tales known as “Le Petit Poucet” (Little Thumbling) by Charles Perrault has been more and more present in the art world.
Martial Poirson
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Sovremennye Issledovaniâ Socialʹnyh Problem, 2015 This article analyzes the views of foreign psycho-pedagogical researchers on a problem of the rite of passage as a tool of sewage for hostile aggression and spiritual and creativity actualization at risk adolescents.
Inga Yuryevna Lebedeva
doaj +1 more source
Personal Expediency of Psychological Resources Actualization
Проблеми сучасної психології, 2021 The aim of the article is to characterize empirically the personal expediency of a person’s actualization of his own psychological resources. In the empirical study, the methods of the psychological questionnaire were used, as well as such methods of ...
Olena Shtepa
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Armenian Folia Anglistika, 2016 The article aims at disclosing the concept God in J. Fowles philosophical essay “The Aristos” as well as defining linguistic means of its actualization.
Heghine Isahakyan
doaj +1 more source
Stochastic make-to-stock inventory deployment problem: an endosymbiotic psychoclonal algorithm based approach [PDF]
, 2006 Integrated steel manufacturers (ISMs) have no specific product, they just produce finished product from the ore. This enhances the uncertainty prevailing in the ISM regarding the nature of the finished product and significant demand by customers.
Birge JR +13 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
“We Need a Showing of All Hands”: Technological Utopianism in \u3cem\u3eMAKE\u3c/em\u3e Magazine [PDF]
, 2011 Make magazine is a quarterly publication focused on do-it-yourself projects involving technology and innovation. The magazine also sponsors a biannual event, the Maker Faire, that brings “makers” together to share their knowledge.
Sivek, Susan Currie
core +1 more source