Results 91 to 100 of about 20,866 (302)
The Effects of Large Premium Increases on Individuals, Families, and Small Businesses [PDF]
Estimates the impact of rising insurance premiums on coverage, costs, adverse selection, public spending, and small employers' offers of insurance under three scenarios.
Bowen Garrett +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
State Retiree Health Care Liabilities: Multiple Factors Contribute to Improving Picture in Many States [PDF]
States paid $18.4 billion in 2013 for worker retirement benefits other than pensions, which are known as other post-employment benefits (OPEB). Almost all of this total was spent on retiree health care.1 The payments covered the cost of current-year ...
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Report of Special Retirement Study Committee [PDF]
The special legislative committee to investigate and study the feasibility of establishing within the State Retirement System thirty year retirement benefits regardless of age for state employees and for teachers and also survivors benefits for teachers,
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Insurance business can be distinguished on some reviews. It includes generalinsurances, life insurances and reinsurances (on the basis of its function).Based on its basic policy, it includes term life insurances, whole life insurances,two beneficial ...
Budi Kolistiawan
doaj +1 more source
How Will the Patient Protection and Affordable Care Act Affect Seniors? [PDF]
Summarizes how healthcare reform provisions including changes to Medicare premiums and drug benefits, preventive services, Medicare Advantage plans; reduced provider payment rates; and efforts to improve quality and system performance will affect ...
John Holahan, Robert A. Berenson
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A Conversation with Ulf Grenander
Ulf Grenander was born in Vastervik, Sweden, on July 23, 1923. He started his undergraduate education at Uppsala University, and earned his B.A. degree in 1946, the Fil. Lic. degree in 1948 and the Fil. Dr.
Mukhopadhyay, Nitis
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

