Results 181 to 190 of about 20,866 (302)

Actuarial Vacancy [PDF]

open access: yesASTIN Bulletin, 2001
openaire   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A unifying theory of aging and mortality. [PDF]

open access: yesSci Rep
Flietner V   +5 more
europepmc   +1 more source

A model framework for projecting the prevalence and impact of Long-COVID in the UK

open access: yes, 2021
Martin C   +5 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Mathematical modeling for glioblastoma treatment: scenario generation and validation for clinical patient counseling. [PDF]

open access: yesFront Oncol
Kostelich EJ   +9 more
europepmc   +1 more source

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