Results 161 to 170 of about 20,866 (302)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Understanding insurance coverage policies for incretin mimetics for weight management. [PDF]

Am J Manag Care
Griauzde DH, Carter EW, Oshman L, Gabison J, Kraftson A, Fendrick AM, Lott S.   +6 more
europepmc   +1 more source

Innovations in mutuality: challenges and learnings for the Universal Health Insurance Plan in Mali. [PDF]

BMJ Glob Health, 2023
Touré L, Boivin P, Diarra Y, Diabaté S, Ridde V.   +4 more
europepmc   +1 more source

Actuarial Vacancy [PDF]

ASTIN Bulletin, 1988
openaire   +1 more source

Will C-36 Undermine CPP "9.9"? Benefit Enhancement and the Sustainability of the Canada Pension Plan [PDF]

The Canada Pension Plan, like all pension plans and social-security programs, is under constant tension. On one side are current and hopeful beneficiaries, who typically want richer payouts.
William B.P. Robson
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Friendly Societies (Miscellaneous) Amendment Act, 1995, No. 86 [PDF]

, 1995

core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Challenges and complications of trans-osseous carpal tenodesis for scapholunate ligament tears. [PDF]

J Hand Microsurg
Räisänen MP, Smith NC, Del Piñal F.
europepmc   +1 more source