Results 151 to 160 of about 3,093 (299)

Exploring and enhancing community awareness on antimicrobial resistance: perspectives from world antimicrobial resistance awareness week celebration in Ghana. [PDF]

BMC Public Health
Loglo AD, Nkrumah-Appau M, Deke J, Asiamah CK, Antwi PB, Newton S, Kotochi S, Nyame MK, Oppong M, Adu CAT, Dorkenoo RM, Sogbo V, Boadi AO, Ayinlooya NEA, Manu S, Amoah B, Ankomah J, Quartey MK, Bansah SE, Essel W, May J, Dekker D, Berg S, Khan N, Akenten CW.   +24 more
europepmc   +1 more source

Ottawa's Pension Gap: The Growing and Under-reported Cost of Federal Employee Pensions [PDF]

Canadian public-sector pension plans typically do not use market yields to calculate their liabilities: if they did, Ottawa’s unfunded pension liability would stand at $227 billion – some $80 billion larger than reported in the Public Accounts. The value
William B.P. Robson, Alexandre Laurin
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Extreme Temperatures, Hospital Utilization and Public Health Insurance Spending. [PDF]

Int J Public Health
Kim Y, Miao Q, Zhu L.
europepmc   +1 more source

Options to Extend Medicare's Trust Fund: Lessons From Japan's Statutory Health Insurance. [PDF]

Inquiry, 2022
Maeda JLK.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Parental beliefs and practices around child weight in London, England: insights from qualitative photo-elicitation interviews. [PDF]

J Public Health (Oxf)
Emmott EH, Bronstone G, Möslinger-Gehmayr V, de Souza-Thomas L, Chin J.   +4 more
europepmc   +1 more source

Physical work exposure matrix for use in the UK Biobank. [PDF]

Occup Med (Lond), 2022
Yanik EL, Stevens MJ, Harris EC, Walker-Bone KE, Dale AM, Ma Y, Colditz GA, Evanoff BA.   +7 more
europepmc   +1 more source

Notional Defined Contribution Pension Systems in a Stochastic Context: Design and Stability [PDF]

Around the world, Pay-As-You-Go (PAYGO) public pension programs face serious long-term fiscal problems due primarily to actual and projected population aging, and most appear unsustainable as currently structured.
Ronald Lee, Alan J. Auerbach
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source