Results 241 to 250 of about 476,790 (282)

Acute-on-chronic liver failure

Challenging Concepts in Critical Care, 2019
This chapter is centred on a case study on acute-on-chronic liver failure. This topic is one of the key challenging areas in critical care medicine and one that all intensive care staff will encounter.
T. Pirani, J. Wendon
semanticscholar   +5 more sources

Plasma exchange for acute and acute-on-chronic liver failure: A systematic review and meta-analysis

Liver transplantation, 2023
Plasma exchange (PE) is a promising therapeutic option in patients with acute liver failure (ALF) and acute-on-chronic liver failure (ACLF). However, the impact of PE on patient survival in these syndromes is unclear.
Azizullah Beran, Mouhand F. H. Mohamed, Mohammad Shaear, T. Nayfeh, M. Mhanna, O. Srour, Mohamad Nawras, Jonathan Mentrose, R. Assaly, C. Kubal, M. Ghabril, Ruben Hernaez, Kavish R. Patidar   +12 more
semanticscholar   +1 more source

Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis

Gut, 2021
Background and aims Acute-on-chronic liver failure (ACLF) is characterised by acute decompensation of cirrhosis associated with organ failures. We systematically evaluated the geographical variations of ACLF across the world in terms of prevalence ...
G. Mezzano, A. Juanola, A. Cárdenas, E. Mezey, J. Hamilton, E. Pose, I. Graupera, P. Ginés, E. Solà, Ruben Hernaez   +9 more
semanticscholar   +1 more source

Liver Transplantation in Acute-on-chronic Liver Failure

Transplantation, 2020
Liver transplantation (LT) has revolutionized outcomes for cirrhotic patients. Current liver allocation policies dictate patients with highest short-term mortality receive the highest priority, thus, several patients become increasingly ill on the waitlist.
Constantine J. Karvellas, Emmanuel Weiss, Emmanuel Weiss, Claire Francoz, Claire Francoz   +4 more
openaire   +3 more sources

Acute-on-Chronic Liver Failure

2021
In the last two decades, a new concept of acute-on-chronic liver failure (ALCF) has emerged as a distinctive condition compared to decompensated cirrhosis. ACLF is associated with excessive systemic inflammatory response in patients with underlying chronic liver disease, leading to acute deterioration of liver function, multi-organ failure, as well as ...
Fernando Alvarez, Marie-Eve Chartier
openaire   +2 more sources

Management of Acute-on-Chronic Liver Failure [PDF]

Seminars in Liver Disease, 2016
Acute-on-chronic liver failure (ACLF) is defined by the occurrence of organ failure(s) other than the liver in patients with cirrhosis. Even though mortality rates are high, there should no longer be reluctance to admit patients with ACLF in the intensive care unit.
François Durand, Mitra K. Nadim
openaire   +2 more sources

Pro: Acute‐on‐chronic liver failure

Liver Transplantation, 2017
Liver Transplantation 23 1318–1324 2017 AASLD.
Solà, Elsa, Ginès, Pere
openaire   +3 more sources

Terlipressin Is Superior to Noradrenaline in the Management of Acute Kidney Injury in Acute on Chronic Liver Failure

Hepatology, 2019
Hepatorenal syndrome (HRS) carries a high short‐term mortality in patients with cirrhosis and acute on chronic liver failure (ACLF). Terlipressin and noradrenaline are routinely used in cirrhosis with HRS and have been found to be equally effective ...
V. Arora, R. Maiwall, V. Rajan, A. Jindal, Saggere Muralikrishna Shasthry, G. Kumar, P. Jain, S. Sarin   +7 more
semanticscholar   +1 more source

Overview on acute-on-chronic liver failure [PDF]

Frontiers of Medicine, 2016
Liver failure (LF) is defined as severe dysfunction in hepatic synthesis, detoxification, and metabolism induced by various etiologies. Clinical presentation of LF typically includes severe jaundice, coagulation disorder, hepatic encephalopathy, and ascites. LF can be classified into acute LF, acute-on-chronic LF (ACLF), and chronic LF.
Ke-Qin Hu, Jing Zhang, Zhongping Duan, Shan Gao   +3 more
openaire   +2 more sources

Liver Transplantation in Acute-on-Chronic Liver Failure

Clinics in Liver Disease, 2023
In recent years there has been a significant increase in the incidence of acute-on-chronic liver failure (ACLF). This syndrome is characterized by infections, organ failures, and high short-term mortality. Although progress in the management of these sick patients has been evident, liver transplantation (LT) remains the best treatment modality to date.
Anand V, Kulkarni, K Rajender, Reddy
openaire   +2 more sources