Successful orthotopic liver transplantation in an adult patient with sickle cell disease and review of the literature [PDF]
Sickle cell disease can lead to hepatic complications ranging from acute hepatic crises to chronic liver disease including intrahepatic cholestasis, and iron overload.
Blinder, Morey A. +7 more
core +2 more sources
Immune mediated liver failure [PDF]
Liver failure is a clinical syndrome of various etiologies, manifesting as jaundice, encephalopathy, coagulopathy and circulatory dysfunction, which result in subsequent multiorgan failure.
Ning, Qin, Wang, Xiaojing
core +1 more source
Use of OKT3 with ciclosporin and steroids for reversal of acute kidney and liver allograft rejection [PDF]
OKT3 monoclonal antibody therapy was added to preexisting baseline immunosuppressive treatment with ciclosporin and steroids to treat rejection in 52 recipients of cadaveric livers and 10 recipients of cadaveric kidneys.
Demetris, AJ, Fung, JJ, Porter, KA
core +1 more source
Liver Transplantation for Acute on Chronic Liver Failure [PDF]
Acute-on chronic liver failure (ACLF) is defined as acute insult on previous liver disease that causes sudden worsening of liver functions.ACLF is characterized by high incidence of organ failure and prognosis is remarkably worse than patients with cirrhosis. Incidence of organ failures is very high despite best medical care and timely liver transplant
Narendra S. Choudhary +3 more
openaire +3 more sources
Dynamic analysis of acute deterioration in chronic liver disease patients using modified quick sequential organ failure assessment [PDF]
Background/Aims Quick sequential organ failure assessment (qSOFA) is believed to identify patients at risk of poor outcomes in those with suspected infection.
Do Seon Song +23 more
doaj +1 more source
Xenobiotic metabolism: the effect of acute kidney injury on non-renal drug clearance and hepatic drug metabolism. [PDF]
Acute kidney injury (AKI) is a common complication of critical illness, and evidence is emerging that suggests AKI disrupts the function of other organs.
Abosaif +82 more
core +2 more sources
BACKGROUND & AIMS Liver transplantation for patients with acute-on-chronic liver failure (ACLF) with 3 or more failing organs (ACLF-3) is controversial. We compared liver waitlist mortality or removal according to model for end-stage liver disease (MELD)
V. Sundaram +6 more
semanticscholar +1 more source
Macrophage Activation Markers, CD163 and CD206, in Acute-on-Chronic Liver Failure
Macrophages facilitate essential homeostatic functions e.g., endocytosis, phagocytosis, and signaling during inflammation, and express a variety of scavenger receptors including CD163 and CD206, which are upregulated in response to inflammation.
M. Nielsen +5 more
semanticscholar +1 more source
Liver Transplantation as a Cornerstone Treatment for Acute-On-Chronic Liver Failure
Acute-on-chronic liver failure (ACLF) is a distinct clinical syndrome, characterized by acute decompensation (AD) of liver cirrhosis, severe systemic inflammation, intra- and extrahepatic organ failures, and a high short-term mortality.
M. Schulz +3 more
semanticscholar +1 more source
Acute decompensation and acute-on-chronic liver failure
Acute decompensation is defined as the development of ascites, bleeding due to portal hypertension, jaundice, or hepatic encephalopathy in the presence of known or unknown chronic liver disease.
Sencan Acar
doaj +1 more source

