Results 91 to 100 of about 435,097 (243)

Rapid and widely disseminated acute phase protein response after experimental bacterial infection of pigs [PDF]

open access: hybrid, 2009
Kerstin Skovgaard   +6 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Acute phase serum proteins in diabetic retinopathy

open access: yesIndian Journal of Ophthalmology, 1996
The serum concentration of various acute phase reactants were studied in patients with non-insulin dependent diabetes mellitus with and without retinopathy and in control subjects.
Rema M, Mohan V, Snehalatha C
doaj  

The Biological Context of C-Reactive Protein as a Prognostic Marker in Renal Cell Carcinoma: Studies on the Acute Phase Cytokine Profile [PDF]

open access: gold, 2020
Helene Hersvik Aarstad   +6 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

PECULARITIES OF COMPOSITION OF PROTEIN FRACTIONS AND ACUTE-PHASE LIQUOR PROTEINS IN NORM AND AT COMPRESSION SYNDROME OF LUMBAR REGION OF SPINE

open access: yesActa Biomedica Scientifica, 2012
Peculiarities of composition of protein fractions and acute-phase liquor proteins as the indications of activity of immunologic liquor reactions were studied by biochemical method in 15 patients without neurological diseases and.
P. G. Gruzin, V. A. Sorokovikov
doaj  

Fecal acute phase proteins in cats with chronic enteropathies. [PDF]

open access: yesJ Vet Intern Med, 2023
Karra DA   +8 more
europepmc   +1 more source

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