Pregnancy diagnosis in the bitch: the development of a test based on the measurement of acute phase proteins in the blood [PDF]
J. S. Evans, DJ Anderton
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Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
The acute phase response of plasma protein synthesis during experimental inflammation.
Gerhard Schreiber+6 more
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Editorial: Acute phase proteins as biomarkers and therapeutics in acute and chronic inflammatory conditions. [PDF]
Stanke F, Janciauskiene S, Olejnicka B.
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Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Circadian disruption and psychostimulants dysregulates plasma acute-phase proteins and circulating cell-free mitochondrial DNA. [PDF]
Ramasamy T+3 more
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Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Two forms of decidualization-associated protein and their physicochemical relationship with acute-phase alphamacrofetoprotein in rats [PDF]
Natércia Teixeira, J. E. O'GRADY
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The Sir David Cuthbertson Medal Lecture 1991:The mechanisms and treatment of weight loss in cancer [PDF]
Ball+27 more
core +1 more source