Results 191 to 200 of about 714,663 (382)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

The acute phase protein, haptoglobin : a potential parameter in welfare assessment? [PDF]

, 2011
Physiological parameters are important measures in animal welfare assessment. To assess the amount of stress an animal experiences, stress hormones like cortisol are frequently used.
Bahr, Claudia, Berckmans, Daniel, De Backer, Kristina, Moons, Christel, Niewold, Theo A, Odberg, Frank, Ott, Sanne   +6 more
core   +1 more source

Hematological Normality, Serum Biochemistry, and Acute Phase Proteins in Healthy Beef Calves in the Brazilian Savannah. [PDF]

Animals (Basel), 2023
Motta GA, Neto PSM, Nociti RP, Santana ÁE.   +3 more
europepmc   +1 more source

The human hepatoma Hep3B cell line as an experimental model in the study of the long-term regulation of acute-phase proteins by cytokines [PDF]

, 1992
Martine Hiron, Maryvonne Daveau, Philippe Arnaúd, Jan Bauer, J. P. Lebreton   +4 more
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Diagnosis of some diseases through biomarkers [PDF]

, 2019
Muchos gatos, como los perros, sufren de diferentes enfermedades. que en ese momento no permiten mostrar síntomas o signos que permiten identificar que la mascota sufre una enfermedad grave, ya que las características de los gatos son diferentes a las de
Gutiérrez Rodríguez, Andrea
core  

Circadian disruption and psychostimulants dysregulates plasma acute-phase proteins and circulating cell-free mitochondrial DNA. [PDF]

Brain Behav Immun Health, 2023
Ramasamy T, Doke M, McLaughlin JP, Samikkannu T.   +3 more
europepmc   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Клинико−биохимические параллели при внутрибрюшных абсцессах после операций на кишечнике [PDF]

, 2005
Проведен сопоставительный анализ клинических данных и результатов биохимического исследования крови больных с внутрибрюшными абсцессами. Установлена динамика показателей белков острой фазы С−реактивного белка, орозомукоида и гаптоглобина.
Антонюк, О.С., Украинский, В.В.   +1 more
core  

Editorial: Acute phase proteins as biomarkers and therapeutics in acute and chronic inflammatory conditions. [PDF]

Front Pharmacol, 2023
Stanke F, Janciauskiene S, Olejnicka B.
europepmc   +1 more source