Results 141 to 150 of about 7,815,815 (291)

The changing burden of long-term health outcomes in survivors of childhood acute lymphoblastic leukaemia: a retrospective analysis of the St Jude Lifetime Cohort Study

, 2019
Daniel A. Mulrooney, Geehong Hyun, Kirsten K. Ness, Nickhill Bhakta, Ching‐Hon Pui, Matthew J. Ehrhardt, Kevin R. Krull, Deborah B. Crom, Wassim Chemaitilly, Deo Kumar Srivastava, Mary V. Relling, Sima Jeha, Daniel M. Green, Yutaka Yasui, Leslie L. Robison, Melissa M. Hudson   +15 more
openalex   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Human Enterovirus 109: a Novel Interspecies Recombinant Enterovirus Isolated from a Case of Acute Pediatric Respiratory Illness in Nicaragua

, 2010
Nathan L. Yozwiak, Peter Skewes-Cox, Aubree Gordon, Saira Saborío, Guillermina Kuan, Ángel Balmaseda, Don Ganem, Eva Harris, Joseph L. DeRisi   +8 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Uloga nuklearne medicine u transplantaciji bubrega [PDF]

Vojnosanitetski Pregled, 2004
Jakšić Emilija D., Beatović Slobodanka L., Han Ruben S.   +2 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Corrigendum: Glycemia Is Related to Impaired Cerebrovascular Autoregulation after Severe Pediatric Traumatic Brain Injury: A Retrospective Observational Study

Frontiers in Pediatrics, 2017
Adam M. H. Young, Hadie Adams, Joseph Donnelly, Mathew R. Guilfoyle, Helen Fernandes, Mathew R. Garnett, Marek Czosnyka, Peter Smielewski, Mark Plummer, Shruti Agrawal, Peter J. Hutchinson   +10 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Therapeutic effect of Qingyi decoction in severe acute pancreatitis-induced intestinal barrier injury

, 2015
Jingwen Zhang
openalex   +2 more sources

Second allogeneic haematopoietic cell transplantation using HLA‐matched unrelated versus T‐cell replete haploidentical donor and survival in relapsed acute myeloid leukaemia [PDF]

, 2021
Mohamed A. Kharfan‐Dabaja, Myriam Labopin, Éolia Brissot, Nicolaus Kröger, Jürgen Finke, Fabio Ciceri, Éric Deconinck, Didier Blaise, Patrice Chevallier, Martin Gramatzki, Arnold Ganser, Matthias Stelljes, Matthias Edinger, Bipin N. Savani, Annalisa Ruggeri, Jaime Sanz, Arnon Nagler, Mohamad Mohty   +17 more
openalex   +1 more source