Results 151 to 160 of about 4,827,497 (316)

Acute flaccid myelitis (AFM) : what health care providers need to know [PDF]

open access: yes
Date: Tuesday, November 13, 2018Time: 2:00pm-3:00pm (Eastern Time)The Centers for Disease Control and Prevention (CDC) is actively investigating acute flaccid myelitis, or AFM, a serious condition that causes weakness in the arms or legs.

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Acute endocrine conditions

open access: yes, 2018
Acute endocrine conditions such as diabetes and thyroid disease are potentially life threat­ening, with high mortality rates if they are not detected and treated rapidly.
Barton, Matthew   +4 more
core   +1 more source

Acute Epiglottitis (Acute Supraglottitis) [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1953
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Acute kidney injury in Australia: a first national snapshot [PDF]

open access: yes, 2015
Overview Acute kidney injury (AKI) is increasing in incidence globally. This report presents the first national statistical snapshot on AKI and its impact in Australia.
Australian Institute of Health and Welfare
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Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Acute Services Operational Plan 2017

open access: yes, 2017
The demand for acute hospital services continues to increase in line with a growing and ageing population. The Hospital Groups continue to implement the Securing the Future of Smaller Hospitals: A Framework for Development.
Acute Services Division. Health Service Executive
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