Results 1 to 10 of about 1,607,516 (246)

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

open access: yesNature Communications
Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands.
GBD 2019 Acute and Chronic Care Collaborators
doaj   +1 more source

Definition and Management of the Immune Tolerance Phase in Chronic Hepatitis B

open access: yesThe Korean Journal of Gastroenterology, 2022
In the natural course of chronic hepatitis B, the immune tolerance phase is characterized by HBeAg positivity, very high levels of HBV DNA, and persistent normal alanine aminotransferase.
Young Mi Hong , Ki Tae Yoon
doaj   +1 more source

Comorbidities and functional disability in chronic low back pain [PDF]

open access: yesOpšta Medicina, 2019
Introduction: Chronic low back pain is a syndrome caused by different anatomical and functional disorders of the lumbar spine and its surroundings, lasting over three months.
Jandrić-Kočić Marijana C.
doaj  

Experimental Traumatic Brain Injury Induces Chronic Glutamatergic Dysfunction in Amygdala Circuitry Known to Regulate Anxiety-Like Behavior

open access: yesFrontiers in Neuroscience, 2020
Up to 50% of traumatic brain injury (TBI) survivors demonstrate persisting and late-onset anxiety disorders indicative of limbic system dysregulation, yet the pathophysiology underlying the symptoms is unclear.
Joshua A. Beitchman   +20 more
doaj   +1 more source

Independent Risk Factors for Hepatocellular Carcinoma Recurrence after Direct-Acting Antiviral Therapy in Patients with Chronic Hepatitis C

open access: yesGut and Liver, 2021
Background/Aims: This study was performed to evaluate the efficacy of direct-acting antivirals (DAAs) in Korean patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC) and to investigate the risk factors associated with HCC ...
Young-Hwan Ahn   +14 more
doaj   +1 more source

Plasma and Urinary Phenolic Profiles after Acute and Repetitive Intake of Wild Blueberry

open access: yesMolecules, 2016
Recent studies have shown that blueberries may have cardiovascular and cognitive health benefits. In this work, we investigated the profile of plasma and urine (poly)phenol metabolites after acute and daily consumption of wild blueberries for 30 days in ...
Rodrigo P. Feliciano   +3 more
doaj   +1 more source

COVID‐19 in Western Australia: ‘The last straw’ and hopes for a ‘new normal’ for parents of children with long‐term conditions

open access: yesHealth Expectations, 2023
Background Children with long‐term conditions are vulnerable due to the treatments required for their conditions. Since the start of the coronavirus disease 2019 (COVID‐19) pandemic, Western Australians experienced restrictions that changed daily life ...
Stephanie Smith   +4 more
doaj   +1 more source

Real-Life Effectiveness and Safety of Sofosbuvir-Based Therapy in Genotype 2 Chronic Hepatitis C Patients in South Korea, with Emphasis on the Ribavirin Dose

open access: yesGut and Liver, 2020
Background/Aims: Sofosbuvir (SOF)-based therapy has been used in Korean patients with chronic hepatitis C virus (HCV) infection since January 2016. This study aimed to investigate the real-life effectiveness and safety of SOF-based therapy in genotype 2 ...
Eun Sun Jang   +7 more
doaj   +1 more source

Long-term Nucleotide Analogue Treatment Has Higher Levels of Renal Toxicities than Does Entecavir in Patients with Chronic Hepatitis B

open access: yesGut and Liver, 2020
Background/Aims: Renal toxicity is a concern in patients with chronic hepatitis B taking nucleotide analogues, such as adefovir (ADV) and tenofovir disoproxil fumarate (TDF).
Young Youn Cho   +8 more
doaj   +1 more source

Cost-effectiveness of telbivudine versus lamivudine for chronic hepatitis B

open access: yesBrazilian Journal of Infectious Diseases
BACKGROUND AND AIM: Chronic hepatitis B is a highly prevalent disease worldwide, leading to serious consequences if not properly treated. Six treatment options for chronic hepatitis B are currently provided by the Brazilian public health system ...
Astrid Wiens   +3 more
doaj   +1 more source

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