Results 171 to 180 of about 6,467,172 (346)
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Art. XXIV.—Test-Types for the Determination of the Acuteness of Vision. [PDF]
H. A. Snellen
openalex +1 more source
A CASE OF PANCREATIC HÆMORRHAGE AND FAT NECROSIS, WITH A CONSIDERATION OF ACUTE INFLAMMATION OF THE PANCREAS. [PDF]
, 1893 HerbertP. Hawkins
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Bipolar-Staining Bacilli of the Fowl-Cholera Type as the Cause of Wide-Spread, Acute, and Fatal Pneumonia in Horse and Donkey Young Stock in India [PDF]
, 1909 E. Clive Webb
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2011 Background and Objectives: Adenosine 5́-triphosphate (ATP) not only is the current energy source of all cells but also plays critical role in triggering signaling pathways leading to apoptosis or differentiation.
M.A Moosavi, A.H Ahmadi, R Yazdanparast
doaj