Results 81 to 90 of about 3,859,259 (322)
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source
Endovascular Treatment of Acute Ischemic Stroke
대한영상의학회지, 2020 Acute ischemic stroke is one of the leading causes of disability and death around the world, especially in developed countries. Since the introduction of the 2nd generation devices, endovascular treatment of acute ischemic stroke has rapidly developed ...
Jun Hwee Kim, Byung Moon Kim
doaj +1 more source
A Dihedral Acute Triangulation of the Cube [PDF]
arXiv, 2009 It is shown that there exists a dihedral acute triangulation of the three-dimensional cube. The method of constructing the acute triangulation is described, and symmetries of the triangulation are discussed.
arxiv
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Acute sets of exponentially optimal size [PDF]
arXiv, 2017 We present a simple construction of an acute set of size $2^{d-1}+1$ in $\mathbb{R}^d$ for any dimension $d$. That is, we explicitly give $2^{d-1}+1$ points in the $d$-dimensional Euclidean space with the property that any three points form an acute triangle. It is known that the maximal number of such points is less than $2^d$.
arxiv
FEBS Letters, EarlyView.Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel +2 more
wiley +1 more source
Improving Recurrent Neural Network Responsiveness to Acute Clinical Events [PDF]
arXiv, 2020 Predictive models in acute care settings must be able to immediately recognize precipitous changes in a patient's status when presented with data reflecting such changes. Recurrent neural networks (RNNs) have become common for training and deploying clinical decision support models. They frequently exhibit a delayed response to acute events.
arxiv
FEBS Letters, EarlyView.Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston +7 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source