Results 71 to 80 of about 316,694 (219)

Impressions of acute pain services in a tertiary care center in India – Enhancing perioperative outcomes beyond pain

open access: yesThe Indian Anaesthetists' Forum
Background and Objective: Acute pain services (APSs) in schema to its name primarily aim to manage acute postoperative pain. A meticulous and comprehensive APS leads to the prevention of acute pain developing into persistent chronic postsurgical pain ...
Jyotsna Agarwal   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Establishing an ED Dedicated Trauma Nurse Program to Improve Trauma Care: Insights from Our Trauma Center

open access: yesNursing: Research and Reviews
Neha Aftab,1,2 Michelle R Maxson,1 Dia R Halalmeh,1,2 E’Lise Harden,1,2 Keerat K Bains,1,2 Mohamed A Hussein,3 James A Cranford,1,4 Kristoffer Ryan Wong,1,2 Patrick R Beer,1,2 Adam C Howell,1,2 Gavin A Huber,1,2 Lindsey D Rieck,1,2 Michael L McCann,1,2 ...
Aftab N   +13 more
doaj  

A clinical study correlating the serum levels of lactate dehydrogenase, C-reactive protein, and lipase with the severity and related complications of acute pancreatitis

open access: yesMuller Journal of Medical Sciences and Research
Background: In addition to Ranson’s criteria, computed tomography severity index (CTSI), and Acute Physiology and Chronic Health Evaluation II score, the presence of local or systemic complications can predict severe acute pancreatitis (AP).
Partha Chakraborty   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Acute alcohol-induced liver injury

open access: yesFrontiers in Physiology, 2012
Alcohol consumption is customary in most cultures and alcohol abuse is common worldwide. For example, more than 50% of Americans consume alcohol, with an estimated 23.1% of Americans participating in heavy and/or binge drinking at least once a month. A
Gavin Edward Arteel
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Estado atual do diagnóstico e tratamento da apendicite aguda na criança: avaliação de 300 casos

open access: yesRevista do Colégio Brasileiro de Cirurgiões
OBJETIVOS: Avaliar o estado atual do diagnóstico e tratamento da apendicite aguda em crianças operadas em dois grandes hospitais quaternários da cidade de São Paulo, no período de 30 meses.
Pedro Félix Vital Jr   +1 more
doaj   +1 more source

Acute Appendicitis in Patients with Acute Leukemia

open access: yesThe Korean Journal of Internal Medicine, 1993
The decision to operate for abdominal pain in patients with leukopenia can be exceedingly difficult. Surgical exploration may be the only effective way to differentiate acute appendicitis from other causes, but it involves considerable risk of infectious complications due to immunosuppression.
Kim, Ki Up   +5 more
openaire   +2 more sources

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