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Acute Surgical Abdomen [PDF]

Journal of Investigative Medicine High Impact Case Reports, 2014
Background . Pulmonary embolism is a common and potentially lethal condition. Most patients who die from massive pulmonary embolism do so within the first few hours of the event.
Nader AL-Mane LRCP & SI MB BCh NUI FCARCSI, Faisal AL-Mane MB BCh MRCPI FRCPC, Zein Abdalla MB BS MS FRCA, Joe McDonnell MB BCh FFARCSI   +3 more
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Expression of miR-101-3p in Gastric Cancer and Its Effects on Invasion, Metastasis, and Angiogenesis of Gastric Cancer Cells by Targeting STC-1 Gene to Regulate PI3K/AKT Signaling Pathway

Zhongliu Fangzhi Yanjiu, 2022
Objective To explore the expression of miR-101-3p in gastric cancer and its mechanism on the invasion, metastasis, and angiogenesis of gastric cancer cells by targeting the STC-1 gene to regulate the PI3K/AKT signaling pathway.
LIU Qiang, SUN Shaoming, WANG Wenjun
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Hydroxytyrosol Inhibits MDSCs and Promotes M1 Macrophages in Mice With Orthotopic Pancreatic Tumor

Frontiers in Pharmacology, 2021
The poor immunotherapy of pancreatic cancer is mainly due to its complex immunosuppressive microenvironment. The Mediterranean diet contributes to low cancer incidence. Hydroxytyrosol (HT) derived from olive oil has multiple health-promoting effects, but
Botao Wang, Botao Wang, Lei Yang, Tianyu Liu, Tianyu Liu, Jing Xun, Yuzhen Zhuo, Lanqiu Zhang, Qi Zhang, Qi Zhang, Ximo Wang, Ximo Wang, Ximo Wang   +12 more
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Saikosaponin D Attenuates Pancreatic Injury Through Suppressing the Apoptosis of Acinar Cell via Modulation of the MAPK Signaling Pathway

Frontiers in Pharmacology, 2021
Chronic pancreatitis (CP) is a progressive fibro-inflammatory syndrome. The damage of acinar cells is the main cause of inflammation and the activation of pancreatic stellate cells (PSCs), which can thereby possibly further aggravate the apoptosis of ...
Caixia Li, Lihua Cui, Lanqiu Zhang, Lei Yang, Yuzhen Zhuo, Jialin Cui, Naiqiang Cui, Shukun Zhang   +7 more
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Isobavachalcone Activates Antitumor Immunity on Orthotopic Pancreatic Cancer Model: A Screening and Validation

Frontiers in Pharmacology, 2022
Pancreatic cancer is accompanied by poor prognosis and accounts for a significant number of deaths every year. Since Psoralea corylifolia L. (PCL) possesses a broad spectrum of bioactivities, it is commonly used in traditional Chinese medicine. The study
Xuanming Liu, Hongbo Zhang, Jianlin Cao, Yuzhen Zhuo, Jiahui Jin, Qiaoying Gao, Xiangfei Yuan, Lei Yang, Dihua Li, Yan Wang, Yan Wang   +10 more
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miR-3065-3p promotes stemness and metastasis by targeting CRLF1 in colorectal cancer

Journal of Translational Medicine, 2021
Background Colorectal cancer is one of the most common malignancy in the world. It has been reported that cancer stem cells (CSCs) serve as the primary drivers of tumorigenesis and tumor progression.
Yifan Li, Jing Xun, Botao Wang, Yuan Ma, Lanqiu Zhang, Lei Yang, Ruifang Gao, Jun Guan, Tianyu Liu, Hejun Gao, Ximo Wang, Qi Zhang   +11 more
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Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway

Frontiers in Pharmacology, 2021
Pancreatic fibrosis is a pathological characteristic of chronic pancreatitis (CP) and pancreatic cancer. Chaihu Guizhi Ganjiang Decoction (CGGD) is a traditional Chinese medicine, which is widely used in the clinical treatment of digestive diseases ...
Lihua Cui, Caixia Li, Ye Shang, Dihua Li, Yuzhen Zhuo, Lei Yang, Naiqiang Cui, Yuhong Li, Shukun Zhang   +8 more
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Histone demethylase KDM6B inhibits breast cancer metastasis by regulating Wnt/β‐catenin signaling

FEBS Open Bio, 2021
Tumor metastasis remains a major challenge for patients with breast cancer. Aberrant epigenetic factor lysine‐specific demethylase 6B (KDM6B) has been associated with tumor progression.
Jing Xun, Ruifang Gao, Botao Wang, Yifan Li, Yuan Ma, Jun Guan, Qi Zhang   +6 more
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Identification of a Four-Gene Metabolic Signature to Evaluate the Prognosis of Colon Adenocarcinoma Patients

Frontiers in Public Health, 2022
BackgroundColon adenocarcinoma (COAD) is a highly heterogeneous disease, thus making prognostic predictions uniquely challenging. Metabolic reprogramming is emerging as a novel cancer hallmark that may serve as the basis for more effective prognosis ...
Yang Zheng, Yang Zheng, Rilige Wu, Ximo Wang, Ximo Wang, Ximo Wang, Chengliang Yin   +6 more
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A novel nomogram for adult primary perihilar cholangiocarcinoma and considerations concerning lymph node dissection

Frontiers in Surgery, 2023
ObjectiveTo construct a reliable nomogram available online to predict the postoperative survival of patients with perihilar cholangiocarcinoma.MethodsData from 1808 patients diagnosed with perihilar cholangiocarcinoma between 2004 and 2015 were extracted
Qi Zhang, Qi Zhang, Zehan Liu, Zehan Liu, Shuangqing Liu, Ming Wang, Xinye Li, Jing Xun, Jing Xun, Xiangyu Wang, Qin Yang, Ximo Wang, Dapeng Zhang, Dapeng Zhang   +13 more
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