Results 1 to 10 of about 309,403 (301)

A Multicenter Study of Acute Abdomen in Children With Acute Lymphoblastic Leukemia: CCCG‐ALL‐2015 [PDF]

Cancer Medicine
Objective Acute abdomen presents a significant challenge in the treatment of childhood acute lymphoblastic leukemia (ALL), potentially leading to treatment failure and treatment‐related mortality.
Wenting Gan, Weina Zhang, Jiaoyang Cai, Xiaofan Zhu, Jie Yu, Peifang Xiao, Ju Gao, Yongjun Fang, Changda Liang, Xue Li, Fen Zhou, Xiaowen Zhai, Xiaoxiao Xu, Xin Tian, Aiguo Liu, Ningling Wang, Jiashi Zhu, Frankie Wai‐Tsoi Cheng, Liangchun Yang, Ge Zhang, Shuhong Shen, Hua Jiang, Lingzhen Wang   +22 more
doaj   +2 more sources

Acute Abdomen

Adolescent medicine (Philadelphia, Pa.)
Abdominal pain is a common complaint in adolescents, and its evaluation is challenging. This article provides a method of evaluating the adolescent with acute abdominal pain, reviews the more common causes that may lead to surgical intervention, and provides algorithms for determining a specific diagnosis and mode of treatment.
Kopitnik NL, Kashyap S, Dominique E.
europepmc   +4 more sources

Expression of miR-101-3p in Gastric Cancer and Its Effects on Invasion, Metastasis, and Angiogenesis of Gastric Cancer Cells by Targeting STC-1 Gene to Regulate PI3K/AKT Signaling Pathway

Zhongliu Fangzhi Yanjiu, 2022
Objective To explore the expression of miR-101-3p in gastric cancer and its mechanism on the invasion, metastasis, and angiogenesis of gastric cancer cells by targeting the STC-1 gene to regulate the PI3K/AKT signaling pathway.
LIU Qiang, SUN Shaoming, WANG Wenjun
doaj   +1 more source

Hydroxytyrosol Inhibits MDSCs and Promotes M1 Macrophages in Mice With Orthotopic Pancreatic Tumor

Frontiers in Pharmacology, 2021
The poor immunotherapy of pancreatic cancer is mainly due to its complex immunosuppressive microenvironment. The Mediterranean diet contributes to low cancer incidence. Hydroxytyrosol (HT) derived from olive oil has multiple health-promoting effects, but
Botao Wang, Botao Wang, Lei Yang, Tianyu Liu, Tianyu Liu, Jing Xun, Yuzhen Zhuo, Lanqiu Zhang, Qi Zhang, Qi Zhang, Ximo Wang, Ximo Wang, Ximo Wang   +12 more
doaj   +1 more source

Metastasis of small cell lung carcinoma to the appendix: A case report and literature review

Journal of Radiation Research and Applied Sciences, 2023
Small cell lung cancer (SCLC) is an aggressive tumor with rapid growth and metastasis. Common sites of metastasis include lymph nodes, adrenal glands, liver, bone, and brain, while gastrointestinal metastasis is less and appendicular metastasis is much ...
Yinghan Liu, Guoxin Guan, Fuwen Luo
doaj   +1 more source

Saikosaponin D Attenuates Pancreatic Injury Through Suppressing the Apoptosis of Acinar Cell via Modulation of the MAPK Signaling Pathway

Frontiers in Pharmacology, 2021
Chronic pancreatitis (CP) is a progressive fibro-inflammatory syndrome. The damage of acinar cells is the main cause of inflammation and the activation of pancreatic stellate cells (PSCs), which can thereby possibly further aggravate the apoptosis of ...
Caixia Li, Lihua Cui, Lanqiu Zhang, Lei Yang, Yuzhen Zhuo, Jialin Cui, Naiqiang Cui, Shukun Zhang   +7 more
doaj   +1 more source

Isobavachalcone Activates Antitumor Immunity on Orthotopic Pancreatic Cancer Model: A Screening and Validation

Frontiers in Pharmacology, 2022
Pancreatic cancer is accompanied by poor prognosis and accounts for a significant number of deaths every year. Since Psoralea corylifolia L. (PCL) possesses a broad spectrum of bioactivities, it is commonly used in traditional Chinese medicine. The study
Xuanming Liu, Hongbo Zhang, Jianlin Cao, Yuzhen Zhuo, Jiahui Jin, Qiaoying Gao, Xiangfei Yuan, Lei Yang, Dihua Li, Yan Wang, Yan Wang   +10 more
doaj   +1 more source

miR-3065-3p promotes stemness and metastasis by targeting CRLF1 in colorectal cancer

Journal of Translational Medicine, 2021
Background Colorectal cancer is one of the most common malignancy in the world. It has been reported that cancer stem cells (CSCs) serve as the primary drivers of tumorigenesis and tumor progression.
Yifan Li, Jing Xun, Botao Wang, Yuan Ma, Lanqiu Zhang, Lei Yang, Ruifang Gao, Jun Guan, Tianyu Liu, Hejun Gao, Ximo Wang, Qi Zhang   +11 more
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Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway

Frontiers in Pharmacology, 2021
Pancreatic fibrosis is a pathological characteristic of chronic pancreatitis (CP) and pancreatic cancer. Chaihu Guizhi Ganjiang Decoction (CGGD) is a traditional Chinese medicine, which is widely used in the clinical treatment of digestive diseases ...
Lihua Cui, Caixia Li, Ye Shang, Dihua Li, Yuzhen Zhuo, Lei Yang, Naiqiang Cui, Yuhong Li, Shukun Zhang   +8 more
doaj   +1 more source

Histone demethylase KDM6B inhibits breast cancer metastasis by regulating Wnt/β‐catenin signaling

FEBS Open Bio, 2021
Tumor metastasis remains a major challenge for patients with breast cancer. Aberrant epigenetic factor lysine‐specific demethylase 6B (KDM6B) has been associated with tumor progression.
Jing Xun, Ruifang Gao, Botao Wang, Yifan Li, Yuan Ma, Jun Guan, Qi Zhang   +6 more
doaj   +1 more source