The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer
Colorectal cancer (CRC) progression is regulated by an immunosuppressive tumor microenvironment, but the epigenetic mechanisms governing this milieu remain unclear. This study identifies the histone demethylase KDM6B as a key regulator of myeloid‐derived
Zhibo Hu +16 more
doaj +1 more source
A taxonomic revision of Camptocerus Dejean (Coleoptera: Curculionidae: Scolytinae) [PDF]
The Neotropical ambrosia beetle genus Camptocerus Dejean was revised. Monophyly of the genus was tested using 66 morphological characters in a cladistic analysis. Camptocerus was recovered as monophyletic and 31 species were recognized.
Cognato, Anthony I., Smith, Sarah M.
core +2 more sources
Novel Coronavirus (2019-nCoV) in Disguise [PDF]
Novel coronavirus (2019-nCoV) pandemic is currently one of the most influential topics as it not only impacts the field of medicine but most importantly, it affects the lives of many individuals throughout the world.
Abideen, Zain U. +4 more
core +2 more sources
The Pentatomidae, or Stink Bugs, of Kansas With a Key to Species (Hemiptera: Heteroptera) [PDF]
Forty eight species of Pentatomidae are listed as occurring in the state of Kansas, nine of these are new state records.
Packauskas, Richard J
core +3 more sources
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Early and late complications of bariatric operation. [PDF]
Weight loss surgery is one of the fastest growing segments of the surgical discipline. As with all medical procedures, postoperative complications will occur. Acute care surgeons need to be familiar with the common problems and their management. Although
Beekley, Alec +3 more
core +1 more source
How to deal with an open abdomen? [PDF]
Appropriate open abdomen treatment is one of the key elements in the management of patients who require decompressive laparotomy or in whom the abdomen is left open prophylactically.
Bjorck, Martin +4 more
core +3 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Descriptions of new luperine genera and species from Mexico : with keys to related taxa (Coleoptera: Chrysomelidae: Galerucinae) [PDF]
The section Scelidites ofthe subtribe Luperina is diagnosed and described. A key is provided to separate the genera within this section. Cyphotarsis Jacoby is reduced to a junior synonym of Metacoryna Jacoby.
Clark, Shawn M.
core +1 more source
Biology and systematics of the New World Phyllocnistis Zeller leafminers of the avocado genus Persea (Lepidoptera, Gracillariidae) [PDF]
Four New World species of Phyllocnistis Zeller are described from serpentine mines in Persea (Family Lauraceae). Phyllocnistis hyperpersea, new species, mines the upper leaf surfaces of avocado, Persea americana Mill., and red bay, Persea borbonia (L ...
Davis, Donald, Wagner, David
core +2 more sources

