Results 51 to 60 of about 98,701 (282)

Acute aortic syndrome: aortic dissection—ascending aortic dissection

, 2018
Aortic dissection, intramural haematoma, and penetrating aortic ulcer can each present as an acute aortic syndrome. If left untreated, acute aortic syndrome carries a high mortality.
Volkmar Falk, Robert Hammerschmidt, Christoph T. Starck   +2 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Type B aortic dissection in Marfan patients after the David procedure: Insights from patient-specific simulationCentral MessagePerspective

JTCVS Open
Objective: An elevated risk of acute type B aortic dissection exists in patients with Marfan syndrome after the David procedure. This study explores hemodynamic changes in the descending aorta postsurgery.
Farshad Tajeddini, MASc, David A. Romero, PhD, Yu Xuan Huang, Tirone E. David, MD, Maral Ouzounian, MD, PhD, Cristina H. Amon, ScD, Jennifer C.Y. Chung, MD, MSc   +6 more
doaj   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Modified Cabrol shunt in surgery for Type A acute aortic dissection

Патология кровообращения и кардиохирургия, 2016
Bleeding after surgery for acute aortic dissection in patients who receive antithrombotic therapy for incorrect diagnosis of acute coronary syndrome is a serious challenge for the surgical team.
С. Ю. Болдырев, В. И. Каледа, А. М. Тришина, З. Э. Текуева, Е. С. Думаньян, А. А. Скопец, К. О. Барбухатти, В. А. Порханов   +7 more
doaj   +1 more source

UBE2O Drives Immune Evasion and Radioimmunotherapy Resistance in Lung Cancer by Degrading CDKL1 to Induce PD‐L1 Transcription

Advanced Science, EarlyView.
UBE2O targets CDKL1 for the degradation to upregulate PD‐L1 expression and promotes resistance to radioimmunotherapy in lung cancer, supporting the potential of targeting UBE2O as a promising therapeutic strategy. ABSTRACT Resistance to radioimmunotherapy is one of the primary causes of treatment failure in lung cancer patients; however, the underlying
Huichan Xue, Xiaohua Jie, Zhiwei Liu, Ruoxin Fang, Shuo Wu, Xiaorong Dong, Shuangbing Xu   +6 more
wiley   +1 more source

Diagnosis, management and mortality in acute aortic syndrome: results of the Spanish Registry of Acute Aortic Syndrome (RESA-II)

, 2016
Background: Recent advances in the diagnosis and treatment of acute aortic syndrome should improve the outcome of this disease. The Spanish Registry of Acute Aortic Syndrome aimed to assess current results in acute aortic syndrome management in a wide ...
Miguel Josa, Francisco Valera, Carlos Ballester, Ibon Rodríguez-Sanchez, Victor X Mosquera, Jose Rozado, Jordi López-Ayerbe, Francisco Domínguez, Alicia Mateo-Martinez, Ruben Fernández-Tarrio, Carlos Ferrera, Francisco Calvo-Iglesias, Francisco Nistal, Covadonga Fernández-Golfin, Aquilino Hurlé, Oscar Gil-Albarova, Antonio Barros, Jose-Alberto San román, Jose Rodríguez-Palomares, Violeta Sanchez, Mercedes González-Molina, Arturo Evangelista, Jose-Antonio García Robles, Pastora Gallego, Carmen Garrote, José Manuel Rabasa, Ricardo Vivancos   +26 more
core   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

Medical management of aortic disease [PDF]

Българска кардиология
Drug therapy is a mandatory component of the treatment of patients with acute and chronic aortic syndromes, regardless of the chosen therapeutic approach (surgical, endovascular, or conservative).
E. Dimitrova, D. Kyuchukov
doaj   +3 more sources

An Interesting Case of Right Sided Haemorrhagic Pleural Effusion

Journal of Clinical and Biomedical Sciences, 2022
Hemorrhagic pleural effusions is common in our clinical practice and its usually due to trauma, malignancy and pulmonary embolism. Other rare causes are Bleeding diathesis, Spontaneous hemopneumothorax, Aortic dissection or rupture, Aneurysm ...
A Anitha, K Prabhakar , BR Sindhu
doaj   +1 more source