Results 111 to 120 of about 3,076,930 (294)

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

Acute Liver Rejection in a Multiple Myeloma Patient Treated with Lenalidomide

, 2020
Herein we present a patient that underwent a liver transplant due to primary biliary cholangitis (PBC) and after 9 years developed multiple myeloma. Following the cessation of mycophenolate mofetil and 2 weeks after lenalidomide treatment was started ...
John Eaton, Iuliana Vaxman, Hee Eun Lee, Morie A. Gertz   +3 more
core   +1 more source

Efficient Cholesteric Liquid Crystal Waveguide Polarizing Splitters for High‐Sensitivity Chip‐Scale Atomic Magnetometry

Advanced Science, EarlyView.
An integrated polarimetry architecture based on a cholesteric liquid crystal waveguide polarization splitter overcomes the volumetric bottleneck in chip‐scale atomic magnetometers. By leveraging Bragg‐selective reflection and total‐internal‐reflection‐induced helicity inversion, this ultrathin device enables efficient circular polarization splitting ...
Zhibo Cui, Chuang Wang, Xiangyang Zhou, Gaopu Hou, Jinsheng Hu, Mao Ye, Xu Xiao, Zhen Chai, Yishi Weng, Yuning Zhang   +9 more
wiley   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Recurrent treatment of refractory acute cellular rejection with alemtuzumab after lung transplantation [PDF]

We present an exceptional case of a lung transplant recipient successfully treated by multiple courses of alemtuzumab for refractory acute cellular rejection (ACR). The patient experienced multiple episodes of ACR following the transplantation procedure.
Hellemons, Merel E.; id_orcid, van Haren, Eva, van Vugt, Lukas K., Wijbenga, Nynke; id_orcid, van der Sijs, Heleen; id_orcid   +4 more
core   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Langerhans Cell Histiocytosis or Acute Cellular Rejection?

Pediatric Transplantation
ABSTRACTBackgroundLangerhans cell histiocytosis (LCH) is a rare malignant disorder of epidermal antigen presenting cells. It is characterized by infiltration of various tissues with dendritic cells (Langerhans cells, LC) that express CD1a or CD207 (langerin), often leading to organ dysfunction. A patient with LCH required liver transplantation (LT) for
Andreas Entenmann, Hubert Kogler, Wolf‐Dietrich Huber, Marita Kölz, A. S. Knisely, Kristijan Skok   +5 more
openaire   +2 more sources

Overcoming skin rejection in composite tissue allotransplantation [PDF]

, 2008
The application of composite tissue techniques is constrained by the susceptibility of skin to rejection. The aim of this thesis is to improve our understanding of skin rejection and find ways to avoid it, in order to enable expansion of the ...
Horner, B., Horner, R.
core  

From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits

Advanced Science, EarlyView.
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang, Meng Chen, Guanchen Li, Ruifeng Liu, Yingxin Wang, Ziran Zhao   +5 more
wiley   +1 more source

The role of C4d and donor specific antibodies in face and hand transplantation—a systematic review

Frontiers in Transplantation
To date, little is known about the mechanisms of rejection in vascularized composite allotransplantation, particularly for antibody mediated rejection.
Lioba Huelsboemer, Jake Moscarelli, Alna Dony, Alna Dony, Sam Boroumand, Alejandro Kochen, Leonard Knoedler, Leonard Knoedler, Catherine T. Yu, Sacha C. Hauc, Viola A. Stögner, Richard N. Formica, Christiane G. Lian, Georg F. Murphy, Bohdan Pomahac, Martin Kauke-Navarro   +15 more
doaj   +1 more source