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British Journal of Clinical Pharmacology, EarlyView.Aims This study aimed to evaluate the long‐term cost‐effectiveness of belatacept vs. tacrolimus as maintenance immunosuppression in adult kidney transplant recipients, focusing on the trade‐off between reduced new‐onset diabetes after transplantation (NODAT), immunological risk and potential renal benefit.
Salvatore Di Maria +2 more
wiley +1 more source
Breaking point: Identifying the factors that predict suspension from school
British Educational Research Journal, EarlyView.Abstract School suspensions are associated with adverse educational and psychosocial outcomes, yet little is known about how structural disadvantage, relational factors, health behaviours, well‐being indicators and school‐level factors jointly predict suspension risk in England.
Stephanie Cahill +5 more
wiley +1 more source
Urinary-Cell mRNA Profile and Acute Cellular Rejection in Kidney Allografts [PDF]
New England Journal of Medicine, 2013 Background—The standard test for the diagnosis of acute rejection in kidney transplants is the renal biopsy. Noninvasive tests would be preferable. Methods—We prospectively collected 4300 urine specimens from 485 kidney-graft recipients from day 3 ...
Manikkam Suthanthiran +2 more
exaly +2 more sources
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Incidence of acute cellular rejection and non-cellular rejection in cardiac transplantation
Transplantation Proceedings, 2004Rejection continues to be one of the leading causes of death during the first year after cardiac transplantation. With the advent of more potent immunosuppressive therapies, the incidence of graft rejection has been reported to be decreasing. Yet, this trend has not been well established due to differences in the interpretation of and the protocols for
S, Subherwal +5 more
openaire +2 more sources
Transplantation, 2014
Mixed rejection in kidney transplantation consists of histologic and/or serological evidence of both cellular and humoral components. As it is not confined to a distinct category in the Banff classification, how to best manage these patients is not clear.
Michelle, Willicombe +7 more
openaire +2 more sources
Mixed rejection in kidney transplantation consists of histologic and/or serological evidence of both cellular and humoral components. As it is not confined to a distinct category in the Banff classification, how to best manage these patients is not clear.
Michelle, Willicombe +7 more
openaire +2 more sources
Acute Cellular and Antibody-Mediated Allograft Rejection
Seminars in Respiratory and Critical Care Medicine, 2013Survival post-lung transplantation remains limited to ∼ 50% at 5 years, far below survival after other solid organ transplants. Allograft rejection is a major cause of this limited survival. At least a third of lung transplant recipients experience acute rejection within 1 year posttransplantation. Acute rejection, though rarely a direct cause of death,
William, McManigle +2 more
openaire +2 more sources
Medullary nephritis in the diagnosis of acute cellular rejection
Pathology - Research and Practice, 2015The purpose of this study was to understand the role of lymphomononuclear inflammation (nephritis) in the renal allograft medulla of transplant recipients with acute dysfunction, by comparing the immunophenotype of inflammatory cells present in the medulla and cortex of kidney graft biopsies.This is a retrospective study of 113 renal allograft needle ...
Iria, Visona +3 more
openaire +2 more sources
Pathology of Acute Cellular Rejection
2016Protocol surveillance endomyocardial biopsies are performed to assess for rejection and thus allow the treatment of rejection prior to symptomatic cardiac dysfunction. The biopsies are performed with decreasing frequency post-transplant, usually stopping at 1–3 years post-transplant.
Desley A. H. Neil, Alexandra J. Rice
openaire +1 more source
Iranian journal of kidney diseases, 2009
The incidence of acute rejection of the kidney allograft in the world has been around 15% during the period between 2001 and 2003. It is clinically defined as an elevation in the level of serum creatinine by more than 0.3 mg/dL and is diagnosed by kidney biopsy.
Mohammad-Reza, Ganji, Behrooz, Broumand
openaire +1 more source
The incidence of acute rejection of the kidney allograft in the world has been around 15% during the period between 2001 and 2003. It is clinically defined as an elevation in the level of serum creatinine by more than 0.3 mg/dL and is diagnosed by kidney biopsy.
Mohammad-Reza, Ganji, Behrooz, Broumand
openaire +1 more source