Results 111 to 120 of about 128,658 (220)

World Trade Center neurotoxicant exposure severity is associated with cortical thinning and regional brain atrophy: a neuroimaging study of general responders at midlife

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Exposure to aerosolized pollutants is a risk factor for cognitive impairment and dementia, but the specific features of exposure‐related neurodegeneration remain unclear. METHODS We measured the World Trade Center Neurotoxicant Exposure Severity Index (WTC‐NESI) in 218 responders and unexposed controls aged 44‐65 years.
Sean A. P. Clouston   +15 more
wiley   +1 more source

Applying machine learning to pharmacovigilance data: A proof‐of‐concept study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3503-3512, October 2026.
Aim Machine learning (ML) applications in pharmacovigilance remain limited and underexplored. Using data from the French National pharmacovigilance database (FNPV), this proof‐of‐concept study aimed to assess the feasibility of using a ML algorithm—eXtreme Gradient Boosting (XGBoost)—combined with SHapley Additive exPlanations (SHAP) analysis, to ...
Romain Barus   +6 more
wiley   +1 more source

Repetitive Transcranial Magnetic Stimulation Combined With Median Nerve Electrical Stimulation for Severe Traumatic Brain Injury

open access: yesBrain and Behavior, Volume 16, Issue 10, October 2026.
Combining top‐down rTMS over the left DLPFC with bottom‐up right median nerve stimulation markedly outperformed either modality alone, awakening 93% of patients with severe TBI by week 4 and improving EEG, hemodynamics, and GCS—supporting dual‐pathway neuromodulation as a safe, high‐efficacy strategy for coma recovery.
Nana Wang, Manrong Li, Guozhen Zhang
wiley   +1 more source

Association of Sarcopenia With Global, Motor, Cognitive, and Swallowing Function Prognosis in Stroke Patients: A Systematic Review and Meta‐Analysis

open access: yesBrain and Behavior, Volume 16, Issue 10, October 2026.
ABSTRACT Objective Sarcopenia has been demonstrated to correlate with the prognosis of stroke. This study aimed to systematically evaluate the impact of sarcopenia on global, motor, cognitive, and swallowing function outcomes in stroke patients. Methods Relevant studies investigating the association between sarcopenia and multidimensional prognostic ...
Dandan Xie, Mingming Ma, Lu Chen
wiley   +1 more source

Coexistence of Ebstein Anomaly and Cerebral Cavernous Malformation: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In most patients who have Ebstein anomaly (EA), neurological symptoms are either associated with thromboembolic episodes or due to arrhythmic complications. Cerebral cavernous malformation (CCM) is a vascular anomaly made up of sinusoidally dilated blood vessels, often presenting with seizure activity or intracranial bleeding.
Nazmin Ahmed   +5 more
wiley   +1 more source

Adverse Reactions Identified after Approval of Novel Medicines: Analysis of 339 New Molecular Entities and Therapeutic Biologics

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1120-1128, October 2026.
Postmarketing safety surveillance data identify safety issues not identified in preapproval clinical trials. We describe the frequency of new safety issues overall and by labeling section and the relationship of the most commonly added safety issues with the cumulative number of prescriptions dispensed via retail pharmacies.
Ellen Pinnow   +14 more
wiley   +1 more source

An Evaluation of the Postvoid Residual Urine Volume in Acute Stroke Patients

open access: yesResearch and Reports in Urology
Kaori Yamashita,1,2 Miyuki Kudo,2 Motoya Ando,2 Hikaru Ashida,2 Takahiro Shiseki,1,3 Satoshi Kubota,1 Tetsushi Sakamoto,1 Masashi Inui1,2 1Department of Urology, Tokyo Women’s Medical University Yachiyo Medical Center, Yachiyo, Japan; 2A ...
Yamashita K   +7 more
doaj  

Assessment of Potential Drug‐Drug Interactions in Hospitalized Patients With Cardiovascular Diseases at Kenyatta National Hospital, Nairobi, Kenya: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aim Drug–drug interactions (DDIs) occur when the pharmacological effect of one medication is altered by the concurrent administration of another, potentially leading to reduced therapeutic efficacy or increased risk of adverse effects.
Brenda Koech, Ermias Terefe
wiley   +1 more source

Exercise and Autonomic Cardiovascular Function—Insights From Spinal Cord‐Injured Humans: A Narrative Review

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT The cardiovascular response to acute exercise is mediated by the autonomic nervous system (ANS) control mechanisms that modulate vascular resistance to support blood pressure and ensure adequate blood flow to active muscles. These autonomic neurocirculatory control mechanisms include a feedforward mechanism, known as central command, and three
Rasmus Kopp Hansen   +5 more
wiley   +1 more source

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