Results 1 to 10 of about 268,686 (304)

Unraveling the Role of α2δ‐1 in Cerebral Hemorrhage: Calcium Overload, Endoplasmic Reticulum Stress, and Microglial Apoptosis [PDF]

Brain and Behavior
Objective Cerebral hemorrhage is a severe condition associated with high morbidity and mortality. Understanding the underlying pathogenesis is crucial for developing effective therapeutic strategies.
Ning Yu, Xiaopeng Li, Bingqian Wang, Chengrui Nan, Qianxu Jin, Liang Yang, Depei Li, Zongmao Zhao   +7 more
doaj   +2 more sources

Research progress on PI3K/Akt signaling pathway and cerebral hemorrhage [PDF]

Xin yixue, 2022
As a classic cell signal transduction pathway, PI3K/Akt pathway plays a role in a variety of biological processes, such as cell growth, proliferation, differentiation and apoptosis.
Yan Meiru, Zhang Yanping, Luo Ruiqi, Wang Siyuan
doaj   +1 more source

Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]

, 2013
Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Arai, Ken, Cianchetti, Flor A., Fan, Xiang, Förch, Christian, Lauer, Arne, Leyen, Klaus van, Lo, Eng H., Mandeville, Emiri, Rosidi, Nathanael L., Schaffer, Chris B., Schlunk, Frieder, Steinmetz, Helmuth, Wang, Xiaoying, Yigitkanli, Kazim   +13 more
core   +8 more sources

Imaging of Intracranial Hemorrhage [PDF]

Journal of Stroke, 2017
Intracranial hemorrhage is common and is caused by diverse pathology, including trauma, hypertension, cerebral amyloid angiopathy, hemorrhagic conversion of ischemic infarction, cerebral aneurysms, cerebral arteriovenous malformations, dural ...
Jeremy J. Heit, Michael Iv, Max Wintermark   +2 more
doaj   +1 more source

Association of CVD candidate gene polymorphisms with ischemic stroke and cerebral hemorrhage in Chinese individuals. [PDF]

PLoS ONE, 2014
BACKGROUND: Contribution of cardiovascular disease related genetic risk factors for stroke are not clearly defined. We performed a genetic association study to assess the association of 56 previously characterized gene variants in 34 candidate genes from
Wenjing Ou, Xin Liu, Yue Shen, Jiana Li, Lingbin He, Yuan Yuan, Xuerui Tan, Lisheng Liu, Jingbo Zhao, Xingyu Wang   +9 more
doaj   +1 more source

A novel intravital method to evaluate cerebral vasospasm in rat models of subarachnoid hemorrhage: a study with synchrotron radiation angiography. [PDF]

PLoS ONE, 2012
Precise in vivo evaluation of cerebral vasospasm caused by subarachnoid hemorrhage has remained a critical but unsolved issue in experimental small animal models. In this study, we used synchrotron radiation angiography to study the vasospasm of anterior
Jun Cai, Yuhao Sun, Falei Yuan, Lujia Chen, Chuan He, Yuhai Bao, Zuoquan Chen, Meiqing Lou, Weiliang Xia, Guo-Yuan Yang, Feng Ling   +10 more
doaj   +1 more source

Novel predictive nomograms for delayed cerebral ischemia and poor neurological function for patients after the Aneurysmal Subarachnoid Hemorrhage: a retrospective study [PDF]

PeerJ
Objective Aneurysmal subarachnoid hemorrhage (aSAH) is a severe stroke subtype often complicated by Delayed Cerebral Ischemia (DCI) and poor neurological outcomes.
Chengqun Lv, Qian Chen, Qianjun Liu, Qinghao Wang, Ming Li, Yu Song, Ming Qiu, Zhengwen Lv, Mingran Zhang, Zhen Li, Yawei Rong, Quan Hu   +11 more
doaj   +2 more sources

Reversal of blood flow in deep cerebral vein in preterm intraventricular hemorrhage: two case reports

BMC Pediatrics, 2020
Background Intraventricular hemorrhage during the early stage is a major complication in very low birth weight infants. Elevation of venous pressure is one of the contributing factors.
Kenichi Tanaka, Rieko Sakamoto, Hiroko Imamura, Tetsuo Naramura, Shirou Matsumoto, Masanori Iwai, Hiroshi Mitsubuchi, Kimitoshi Nakamura   +7 more
doaj   +1 more source

Familial multiple cavernous malformation syndrome : MR features in this uncommon but silent threat [PDF]

, 2016
Cerebral cavernous malformations (CCM) are vascular malformations in the brain and spinal cord. The familial form of cerebral cavernous malformation (FCCM) is uncommon.
Lemmerling, Marc, Mespreuve, Marc, Vanhoenacker, Filip   +2 more
core   +3 more sources

Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. [PDF]

, 2015
PurposeThe phenotypic manifestations of cerebral cavernous malformation disease caused by rare PDCD10 mutations have not been systematically examined, and a mechanistic link to Rho kinase-mediated hyperpermeability, a potential therapeutic target, has ...
Akers, Amy L, Austin, Cecilia, Awad, Issam A, De Souza, Jorge Marcondes, Gallione, Carol J, Gunel, Murat, Lee, Connie, Marchuk, Douglas A, McDonald, David A, Mikati, Abdul Ghani, Min, Wang, Rebeiz, Tania, Rorrer, Autumn, Shenkar, Robert, Shi, Changbin, Stockton, Rebecca A, Zhang, Lingjiao   +16 more
core   +2 more sources