Results 1 to 10 of about 1,668,775 (361)
Advanced Science, 2023 Nerve guidance conduits (NGCs) have become a promising alternative for peripheral nerve regeneration; however, the outcome of nerve regeneration and functional recovery is greatly affected by the physical, chemical, and electrical properties of NGCs.
Ting Zhang, , Chengjin Wang
exaly +2 more sources
The role of exercise on peripheral nerve regeneration: from animal model to clinical application
Heliyon, 2021 Peripheral nerve injury is a complex condition with a variety of signs and symptoms depending on the severity and nerves involved. Peripheral nerve damage may lead to sensory and motor functions deficits and even lifelong disability, causing important ...
Vecchio M +2 more
exaly +2 more sources
Journal of Cellular and Molecular Medicine, 2019 Peripheral nerve injury results in limited nerve regeneration and severe functional impairment. Mesenchymal stem cells (MSCs) are a remarkable tool for peripheral nerve regeneration.
Chaoming Mao +2 more
exaly +2 more sources
The gut metabolite indole-3 propionate promotes nerve regeneration and repair
Nature, 2022 The regenerative potential of mammalian peripheral nervous system neurons after injury is critically limited by their slow axonal regenerative rate1. Regenerative ability is influenced by both injury-dependent and injury-independent mechanisms2.
Elisabeth Serger +18 more
semanticscholar +1 more source
Self-renewing macrophages in dorsal root ganglia contribute to promote nerve regeneration
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance Peripheral sensory neurons situated in dorsal root ganglia (DRG) switch to a regenerative state after nerve injury to enable nerve repair. Axon regeneration is not cell autonomous and is highly influenced by nonneuronal cells.
Rui Feng +3 more
semanticscholar +1 more source
A Bioinspired Self‐Healing Conductive Hydrogel Promoting Peripheral Nerve Regeneration
Advancement of science, 2023 The development of self‐healing conductive hydrogels is critical in electroactive nerve tissue engineering. Typical conductive materials such as polypyrrole (PPy) are commonly used to fabricate artificial nerve conduits.
Hongyun Xuan +8 more
semanticscholar +1 more source
Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration
Cell Metabolism, 2023 Summary The peripheral nervous system harbors a remarkable potential to regenerate after acute nerve trauma. Full functional recovery, however, is rare and critically depends on peripheral nerve Schwann cells that orchestrate breakdown and resynthesis of
Venkat Krishnan Sundaram +27 more
semanticscholar +1 more source
Cells, 2022 The pleiotropic role of the major histocompatibility complex class I (MHC-I) reflects the close association between the nervous and immune systems. In turn, MHC-I upregulation postinjury is associated with a better regenerative outcome in isogenic mice ...
Bruno Henrique de Melo Lima +3 more
doaj +1 more source
Enhanced peripheral nerve regeneration by mechano-electrical stimulation
bioRxiv, 2023 To address limitations in current approaches for treating large peripheral nerve defects, the presented study evaluated the feasibility of functional material-mediated physical stimuli on peripheral nerve regeneration.
Youyi Tai +5 more
semanticscholar +1 more source
Advancement of science, 2022 Peripheral nerve injury is a challenging orthopedic condition that can be treated by autograft transplantation, a gold standard treatment in the current clinical setting.
Zhi Yao +14 more
semanticscholar +1 more source