An organized 3D in vitro model for peripheral nerve studies [PDF]
Three-dimensional cell cultures have been proposed to address the limitations in two-dimensional cell cultures (i.e. lack of relevant architectural features) and very few have developed 3D cell culture methods for peripheral nerve studies. Therefore, the
Daud, Muhammad Fauzi
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Nerve commitment in Hydra. I. Role of morphogenetic signals [PDF]
The kinetics of nerve commitment during head regeneration in Hydra were investigated using a newly developed assay for committed cells. Committed nerve precursors were assayed by their ability to continue nerve differentiation following explanation of ...
Venugopal, G., David, Charles N.
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Nerve commitment in Hydra. II. Localization of commitment in S phase [PDF]
The kinetics of nerve differentiation were investigated during head regeneration in Hydra. In particular the cell cycle parameters of stem cells undergoing nerve commitment were determined.
Venugopal, G., David, Charles N.
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Microglial responses around intrinsic CNS neurons are correlated with axonal regeneration [PDF]
Background: Microglia/macrophages and lymphocytes (T-cells) accumulate around motor and primary sensory neurons that are regenerating axons but there is little or no microglial activation or T-cell accumulation around axotomised intrinsic CNS neurons ...
Bernadette ZY Wong +20 more
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Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation
Activation of mitophagy was considered to be a potential therapeutic strategy for intervertebral disc degeneration (IDD). There was evidence suggesting that hyaluronic acid (HA) can protect mitochondria from oxidative stress in chondrocytes, but its ...
Fu Zhang +11 more
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Nerve Regeneration and Nerve Suture [PDF]
n ...
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An Investigation on the Regeneration of Nerves [PDF]
n ...
Kilvington, Basil, Camp, C. D.
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Advances and Pitfalls of Cell Therapy in Metabolic Leukodystrophies
Leukodystrophies are a group of disorders characterized by myelin dysfunction, either at the level of myelin formation or maintenance, that affect the central nervous system (CNS) and also in some cases, to a lesser extent, the peripheral nervous system (
Catarina Oliveira Miranda +3 more
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Willin, an upstream component of the Hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts [PDF]
Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional coactivator
Tilston-Lünel, A.M. +45 more
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c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration. [PDF]
The radical response of peripheral nerves to injury (Wallerian degeneration) is the cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in Schwann cells is a global regulator of Wallerian degeneration.
Jenkins, Billy +35 more
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