Results 11 to 20 of about 1,744,648 (406)
HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease
Frontiers in Molecular Neuroscience, 2023 IntroductionIn Krabbe disease (KD), mutations in β-galactosylceramidase (GALC), a lysosomal enzyme responsible for the catabolism of galactolipids, leads to the accumulation of its substrates galactocerebroside and psychosine.
Sandra O. Braz +8 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Peripheral nerve injury (PNI) is a common disease in clinic, and the regeneration process of peripheral nerve tissue is slow, and patients with PNI often suffer from the loss of nerve function.
Sulong Wang, Xilin Liu, Yueshu Wang
semanticscholar +1 more source
Pure-silk fibroin hydrogel with stable aligned micropattern toward peripheral nerve regeneration
Nanotechnology Reviews, 2021 Successful repair of long-distance peripheral nerve injuries remains a challenge in the clinic. Rapid axon growth is a key to accelerate nerve regeneration.
Gu Xinyi +6 more
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Mesenchymal Stem Cell Treatment Perspectives in Peripheral Nerve Regeneration: Systematic Review
International Journal of Molecular Sciences, 2021 Traumatic peripheral nerve lesions affect hundreds of thousands of patients every year; their consequences are life-altering and often devastating and cause alterations in movement and sensitivity.
Andrea Lavorato +11 more
semanticscholar +1 more source
The Role of Neurotropic B Vitamins in Nerve Regeneration
BioMed Research International, 2021 Damage and regeneration naturally occur in the peripheral nervous system. The neurotropic B vitamins thiamine (B1), pyridoxine (B6), and cobalamin (B12) are key players, which maintain the neuronal viability in different ways.
S. Baltrusch
semanticscholar +1 more source
Optic Nerve Regeneration [PDF]
Archives of Ophthalmology, 2010 Retinal ganglion cells are usually not able to regenerate their axons after optic nerve injury or degenerative disorders, resulting in lifelong visual loss. This situation can be partially reversed by activating the intrinsic growth state of retinal ganglion cells, maintaining their viability, and counteracting inhibitory signals in the extracellular ...
Larry I, Benowitz, Yuqin, Yin
openaire +2 more sources
Nano-Engineered Environment for Nerve Regeneration: Scaffolds, Functional Molecules and Stem Cells [PDF]
, 2016 One of the most complex systems in the human body is the nervous system, which is divided into the central and peripheral nervous systems. The regeneration of the CNS is a complex and challenging biological phenomenon hindered by the low regenerative ...
Ramakrishna, S +7 more
core +12 more sources
The role of exercise on peripheral nerve regeneration: from animal model to clinical application
Heliyon, 2021 Peripheral nerve injury is a complex condition with a variety of signs and symptoms depending on the severity and nerves involved. Peripheral nerve damage may lead to sensory and motor functions deficits and even lifelong disability, causing important ...
Grazia Maugeri +7 more
semanticscholar +1 more source
Cortical plasticity and nerve regeneration after peripheral nerve injury
Neural Regeneration Research, 2021 With the development of neuroscience, substantial advances have been achieved in peripheral nerve regeneration over the past decades. However, peripheral nerve injury remains a critical public health problem because of the subsequent impairment or ...
Ci Li +3 more
semanticscholar +1 more source
Interdisciplinary Neurosurgery, 2021 Peripheral nerve trauma impacts both social and occupational quality of life. Patients are typically young and subsequently suffer from lifelong disability.
Saad Javeed +4 more
semanticscholar +1 more source