Results 21 to 30 of about 784,496 (306)
Analysis of the C/EBP family of transcription factors in neuronal repair [PDF]
PhDNeurons within the peripheral nervous system (PNS) have a remarkable ability to repair themselves after injury; however, neurons within the central nervous system (CNS) do not spontaneously regenerate.
López de Heredia, Luis
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Mice lacking protease nexin-1 show delayed structural and functional recovery after sciatic nerve crush [PDF]
Multiple molecular mechanisms influence nerve regeneration. Because serine proteases were shown to affect peripheral nerve regeneration, we performed nerve crush experiments to study synapse reinnervation in adult mice lacking the serpin protease nexin-1
Atanasoski, Suzana +7 more
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Background: Intervertebral disc degeneration (IDD) is the leading cause of lower back pain, and an overall understanding of the molecular mechanisms related to IDD is still lacking. The purpose of this study was to explore gene signatures and immune cell
Tao Tang +17 more
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Nerve cell differentiation in hydra requires two signals [PDF]
Endogenous signals controlling nerve cell commitment in hydra were investigated using an assay for committed nerve precursors. Extracts of hydra tissue were prepared and tested for their ability to induce nerve cell commitment.
Schaller, Chica H. +2 more
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Biodegradable hydrogels as scaffolds for nerve regeneration [PDF]
Biodegradable hydrogels as scaffolds for nerve regeneration Valerio Magnaghi 1, Elisabetta Ranucci 2, Fabio Fenili 2, Patrizia Procacci 3, Giorgio Pivato 4, Paolo Cortese 4 and Paolo Ferruti 2 1 Department of Endocrinology, Physiopathology ...
V. Magnaghi +6 more
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In Krabbe's disease (KD), a leukodystrophy caused by β-galactosylceramidase deficiency, demyelination and a myelin-independent axonopathy contributes to the severe neuropathology.
Carla Andreia Teixeira +8 more
doaj +1 more source
Preclinical study of peripheral nerve regeneration using nerve guidance conduits based on polyhydroxyalkanaotes [PDF]
Nerve guidance conduits (NGCs) are used as an alternative to the “gold standard” nerve autografting, preventing the need for surgical intervention required to harvest autologous nerves.
Lizarraga Valderrama, L. +22 more
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Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Initial Segment
By binding to actin filaments, non-muscle myosin II (NMII) generates actomyosin networks that hold unique contractile properties. Their dynamic nature is essential for neuronal biology including the establishment of polarity, growth cone formation and ...
Ana Rita Costa, Monica M. Sousa
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In the adult nervous system axon caliber varies widely amongst different tracts. When considering a given axon, its diameter can further fluctuate in space and time, according to processes including the distribution of organelles and activity-dependent ...
Ana Rita Costa +4 more
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The Role of Spastin in Axon Biology
Neurons are highly polarized cells with elaborate shapes that allow them to perform their function. In neurons, microtubule organization—length, density, and dynamics—are essential for the establishment of polarity, growth, and transport. A mounting body
Ana Catarina Costa +2 more
doaj +1 more source

