Results 21 to 30 of about 784,496 (306)

Analysis of the C/EBP family of transcription factors in neuronal repair [PDF]

open access: yes, 2009
PhDNeurons within the peripheral nervous system (PNS) have a remarkable ability to repair themselves after injury; however, neurons within the central nervous system (CNS) do not spontaneously regenerate.
López de Heredia, Luis
core   +4 more sources

Mice lacking protease nexin-1 show delayed structural and functional recovery after sciatic nerve crush [PDF]

open access: yes, 2007
Multiple molecular mechanisms influence nerve regeneration. Because serine proteases were shown to affect peripheral nerve regeneration, we performed nerve crush experiments to study synapse reinnervation in adult mice lacking the serpin protease nexin-1
Atanasoski, Suzana   +7 more
core   +1 more source

Identification of novel gene signatures and immune cell infiltration in intervertebral disc degeneration using bioinformatics analysis

open access: yesFrontiers in Molecular Biosciences, 2023
Background: Intervertebral disc degeneration (IDD) is the leading cause of lower back pain, and an overall understanding of the molecular mechanisms related to IDD is still lacking. The purpose of this study was to explore gene signatures and immune cell
Tao Tang   +17 more
doaj   +1 more source

Nerve cell differentiation in hydra requires two signals [PDF]

open access: yes, 1986
Endogenous signals controlling nerve cell commitment in hydra were investigated using an assay for committed nerve precursors. Extracts of hydra tissue were prepared and tested for their ability to induce nerve cell commitment.
Schaller, Chica H.   +2 more
core   +1 more source

Biodegradable hydrogels as scaffolds for nerve regeneration [PDF]

open access: yes, 2010
Biodegradable hydrogels as scaffolds for nerve regeneration Valerio Magnaghi 1, Elisabetta Ranucci 2, Fabio Fenili 2, Patrizia Procacci 3, Giorgio Pivato 4, Paolo Cortese 4 and Paolo Ferruti 2 1 Department of Endocrinology, Physiopathology ...
V. Magnaghi   +6 more
core   +2 more sources

Early axonal loss accompanied by impaired endocytosis, abnormal axonal transport, and decreased microtubule stability occur in the model of Krabbe's disease

open access: yesNeurobiology of Disease, 2014
In Krabbe's disease (KD), a leukodystrophy caused by β-galactosylceramidase deficiency, demyelination and a myelin-independent axonopathy contributes to the severe neuropathology.
Carla Andreia Teixeira   +8 more
doaj   +1 more source

Preclinical study of peripheral nerve regeneration using nerve guidance conduits based on polyhydroxyalkanaotes [PDF]

open access: yes, 2021
Nerve guidance conduits (NGCs) are used as an alternative to the “gold standard” nerve autografting, preventing the need for surgical intervention required to harvest autologous nerves.
Lizarraga Valderrama, L.   +22 more
core   +1 more source

Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Initial Segment

open access: yesCells, 2020
By binding to actin filaments, non-muscle myosin II (NMII) generates actomyosin networks that hold unique contractile properties. Their dynamic nature is essential for neuronal biology including the establishment of polarity, growth cone formation and ...
Ana Rita Costa, Monica M. Sousa
doaj   +1 more source

The Regulation of Axon Diameter: From Axonal Circumferential Contractility to Activity-Dependent Axon Swelling

open access: yesFrontiers in Molecular Neuroscience, 2018
In the adult nervous system axon caliber varies widely amongst different tracts. When considering a given axon, its diameter can further fluctuate in space and time, according to processes including the distribution of organelles and activity-dependent ...
Ana Rita Costa   +4 more
doaj   +1 more source

The Role of Spastin in Axon Biology

open access: yesFrontiers in Cell and Developmental Biology, 2022
Neurons are highly polarized cells with elaborate shapes that allow them to perform their function. In neurons, microtubule organization—length, density, and dynamics—are essential for the establishment of polarity, growth, and transport. A mounting body
Ana Catarina Costa   +2 more
doaj   +1 more source

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