Results 31 to 40 of about 118,456 (317)

Identification of hub genes related to the innate immune response activated during spinal cord injury

FEBS Open Bio, 2022
Spinal cord injury (SCI) often leads to sensory and motor dysfunction. Two major factors that hinder spinal cord repair are local inflammation and glial scar formation after SCI, and thus appropriate immunotherapy may alleviate damage.
Jianfeng Li, Xizhe Liu, Huachuan Wu, Peng Guo, Baoliang Li, Jianmin Wang, Wei Tian, Dafu Chen, Manman Gao, Zhiyu Zhou, Shaoyu Liu   +10 more
doaj   +1 more source

REGENERATION OF PERIPHERAL NERVES [PDF]

The Journal OF Nervous and Mental Disease, 1922
n ...
openaire   +2 more sources

Endocannabinoid System Modulates Glial Responses and Motoneuron Preservation After Spinal Cord Ventral Root Axotomy

Neuroglia
Background/Objectives: Injuries to spinal ventral roots induce complex retrograde reactions that compromise motoneuron survival, synaptic organization, and glial responses, ultimately limiting the potential for regeneration.
Caroline Machado Tomazelli, Alexandre Leite Rodrigues de Oliveira, Luciana Politti Cartarozzi   +2 more
doaj   +1 more source

Intradiscal injection for the management of low back pain

JOR Spine, 2022
Low back pain (LBP) is a common clinical problem and a major cause of physical disability, imposing a prominent socioeconomic burden. Intervertebral disc degeneration (IDD) has been considered the main cause of LBP.
Fu Zhang, Songjuan Wang, Baoliang Li, Wei Tian, Zhiyu Zhou, Shaoyu Liu   +5 more
doaj   +1 more source

Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation

Frontiers in Cell and Developmental Biology, 2021
Transthyretin (TTR), a plasma and cerebrospinal fluid protein, increases axon growth and organelle transport in sensory neurons. While neurons extend their axons, the microtubule (MT) cytoskeleton is crucial for the segregation of functional compartments
Jessica Eira, Jessica Eira, Joana Magalhães, Nídia Macedo, Maria Elena Pero, Maria Elena Pero, Thomas Misgeld, Mónica M. Sousa, Francesca Bartolini, Márcia A. Liz   +9 more
doaj   +1 more source

Spatial pattern of nerve differentiation in Hydra is due to a pattern of nerve commitment [PDF]

, 1981
The pattern of nerve differentiation along the body column of Hydra was investigated. Nerve precursors in late S phase were labeled with [3H]thymidine and their distribution compared with that of newly differentiated nerves.
G. Venugopal, Venugopal, G., Charles N. David, David, Charles N.   +3 more
core   +1 more source

Neuroprotection and immunomodulation after treatment with NeuroBoost and NeuroHeal following ventral root crush in mice

IBRO Neuroscience Reports
Pharmacological immunomodulation can prevent neuronal loss and reactive gliosis after injuries to spinal nerve roots. NeuroBoost (NB) and NeuroHeal (NH) were used to compare their effects on neuronal survival, glial and immune response, and functional ...
Lilian de Oliveira Coser, Maria Fernanda Vannucci, Júlia Lombardi, Luciana Politti Cartarozzi, Alexandre Leite Rodrigues de Oliveira   +4 more
doaj   +1 more source

Microglial responses around intrinsic CNS neurons are correlated with axonal regeneration

, 2010
Background: Microglia/macrophages and lymphocytes (T-cells) accumulate around motor and primary sensory neurons that are regenerating axons but there is little or no microglial activation or T-cell accumulation around axotomised intrinsic CNS neurons ...
Bernadette ZY Wong, Shokouhi, B.N., Lieberman, A.R., Tohyama, K., Wong Bernadette ZY, Campbell, G., Koujiro Tohyama, Anderson Patrick N, Gregor Campbell, Tohyama Koujiro, Campbell Gregor, Samir Siddiqui, Siddiqui, S., Patrick N Anderson, A Robert Lieberman, Bahman N Shokouhi, Wong, B.Z.Y., Shokouhi Bahman N, Anderson, P.N., Lieberman A Robert, Siddiqui Samir   +20 more
core   +1 more source

Combination of Adult Mesenchymal Stem Cell Therapy and Immunomodulation with Dimethyl Fumarate Following Spinal Cord Ventral Root Repair

Biology
Spinal cord injury results in significant motor and sensory loss. In the experimental ventral root avulsion (VRA) model, the ventral (motor) roots are disconnected from the spinal cord surface, disrupting contact between spinal motoneurons and muscle ...
Paula Regina Gelinski Kempe, Mateus Vidigal de Castro, Lilian de Oliveira Coser, Luciana Politti Cartarozzi, Benedito Barraviera, Rui Seabra Ferreira, Alexandre Leite Rodrigues de Oliveira   +6 more
doaj   +1 more source

ON THE REGENERATION OF NERVES.

The Lancet, 1897
Abstract The author treats the subject under the following heads:— I. A short historical and critical review of the books and papers which have appeared on the subject from the time of Cruik-shank (1776). II. Clinical reports of four cases of secondary suture of nerves as follows:— 1.
openaire   +2 more sources