Results 1 to 10 of about 224,860 (308)
eLife, 2016 The mechanisms regulating synapse numbers during development and ageing are essential for normal brain function and closely linked to brain disorders including dementias. Using Drosophila, we demonstrate roles of the microtubule-associated protein Tau in
Andre Voelzmann +6 more
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microRNAs in axon guidance [PDF]
Frontiers in Cellular Neuroscience, 2014 Brain wiring is a highly intricate process in which trillions of neuronal connections are established. Its initial phase is particularly crucial in establishing the general framework of neuronal circuits. During this early step, differentiating neurons extend axons, which reach their target by navigating through a complex environment with extreme ...
Iyer, A. N., Bellon, A., Baudet, M. L.
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Frontiers in Surgery, 2022 Facial nerve trauma often leads to disfiguring facial muscle paralysis. Despite several promising advancements, facial nerve repair procedures often do not lead to complete functional recovery.
Dmitriy Petrov +14 more
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RNA TRANSLATION IN AXONS [PDF]
Annual Review of Cell and Developmental Biology, 2004 ▪ Abstract The cell body has classically been considered the exclusive source of axonal proteins. However, significant evidence has accumulated recently to support the view that protein synthesis can occur in axons themselves, remote from the cell body.
Piper, M., Holt, C.
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Frontiers in Neuroanatomy, 2018 In this article, we describe the method that allows fluorescently tagged structures such as axons to be targeted for electron microscopy (EM) analysis without the need to convert their labels into electron dense stains, introduce any fiducial marks, or ...
Catherine Maclachlan +4 more
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The Genetics of Axonal Transport and Axonal Transport Disorders
PLoS Genetics, 2006 Neurons are specialized cells with a complex architecture that includes elaborate dendritic branches and a long, narrow axon that extends from the cell body to the synaptic terminal. The organized transport of essential biological materials throughout the neuron is required to support its growth, function, and viability.
Jason E Duncan, Lawrence S B Goldstein
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Neural Development, 2019 Axons are the slender, cable-like, up to meter-long projections of neurons that electrically wire our brains and bodies. In spite of their challenging morphology, they usually need to be maintained for an organism's lifetime.
Ines Hahn +4 more
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FASEB BioAdvancesThis study characterizes a fluorescent Slc17a6‐tdTomato neuronal reporter mouse line with strong labeling of axons throughout the optic nerve, of retinal ganglion cell (RGC) soma in the ganglion cell layer (GCL), and of RGC dendrites in the inner ...
Puttipong Sripinun +8 more
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Polybrominated diphenyl ethers perturb axonal growth and actin distribution
Bibechana, 2018 We investigated toxicological effects of two of the most common polybrominated diphenyl ether (PBDE) flame retardants, BDE-47 and BDE-209, in model PC12 cell line under two environmentally relevant exposure conditions: long term exposure to microgram ...
Bhanu B Neupane +4 more
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Frontiers in Computational Neuroscience, 2020 Advances in computation and neuronal modeling have enabled the study of entire neural tissue systems with an impressive degree of biological realism. These efforts have focused largely on modeling dendrites and somas while largely neglecting axons.
Clayton S. Bingham +5 more
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