Results 1 to 10 of about 228,091 (312)

Studying Axon-Astrocyte Functional Interactions by 3D Two-Photon Ca2+ Imaging: A Practical Guide to Experiments and “Big Data” Analysis

Frontiers in Cellular Neuroscience, 2018
Recent advances in fast volumetric imaging have enabled rapid generation of large amounts of multi-dimensional functional data. While many computer frameworks exist for data storage and analysis of the multi-gigabyte Ca2+ imaging experiments in neurons ...
Iaroslav Savtchouk, Giovanni Carriero, Andrea Volterra   +2 more
doaj   +1 more source

Connexin: a potential novel target for protecting the central nervous system?

Neural Regeneration Research, 2015
Connexin subunits are proteins that form gap junction channels, and play an important role in communication between adjacent cells. This review article discusses the function of connexins/hemichannels/gap junctions under physiological conditions, and ...
Hong-yan Xie, Yu Cui, Fang Deng, Jia-chun Feng   +3 more
doaj   +1 more source

Dipolar extracellular potentials generated by axonal projections

eLife, 2017
Extracellular field potentials (EFPs) are an important source of information in neuroscience, but their physiological basis is in many cases still a matter of debate.
Thomas McColgan, Ji Liu, Paula Tuulia Kuokkanen, Catherine Emily Carr, Hermann Wagner, Richard Kempter   +5 more
doaj   +1 more source

Axon morphology and intrinsic cellular properties determine repetitive transcranial magnetic stimulation threshold for plasticity

Frontiers in Cellular Neuroscience
IntroductionRepetitive transcranial magnetic stimulation (rTMS) is a widely used therapeutic tool in neurology and psychiatry, but its cellular and molecular mechanisms are not fully understood.
Christos Galanis, Lena Neuhaus, Nicholas Hananeia, Zsolt Turi, Peter Jedlicka, Andreas Vlachos, Andreas Vlachos, Andreas Vlachos   +7 more
doaj   +1 more source

Information flow drives localized morphological differences across neuronal and glial cell types

Frontiers in Computational Neuroscience
Neuron processes—axons and dendrites—have distinct branching patterns related to their biological function in the brain and body. Other non-neuronal cells in the nervous system, glia, also have characteristic branching morphologies. Our previous work has
Paheli Desai-Chowdhry, Paheli Desai-Chowdhry, Alexander B. Brummer, Samhita Mallavarapu, Samhita Mallavarapu, Masai Oakes, Van M. Savage, Van M. Savage, Van M. Savage   +8 more
doaj   +1 more source

Transcriptomic and morphological characterization reveals distinct regeneration kinetics in immediate versus delayed nerve repair

Neural Regeneration Research
Peripheral nerve injury is a significant clinical challenge due to its limited regenerative capacity. While immediate repair is generally preferred, delayed repair is often necessary in clinical scenarios where primary intervention is not feasible ...
Marina García-Bejarano, Federica Zen, Marwa El Soury, Alessandro Camandona, Jesús M. de la Fuente, Isabelle Perroteau, Giulia Ronchi, Giulio Ferrero, Giovanna Gambarotta   +8 more
doaj   +1 more source

A simple and inexpensive laser dissection of fasciculated axons from motor nerve organoids

Frontiers in Bioengineering and Biotechnology
Motor nerve organoids could be generated by culturing a spheroid of motor neurons differentiated from human induced pluripotent stem (iPS) cells within a polydimethylsiloxane (PDMS) chip which guides direction and fasciculation of axons extended from the
Yasuhiro Ikegami, Yasuhiro Ikegami, Tomoya Duenki, Tomoya Duenki, Tomoya Duenki, Tomoya Duenki, Ikuma Arakaki, Ikuma Arakaki, Ryo Sakai, Ryo Sakai, Tatsuya Osaki, Tatsuya Osaki, Satoshi Ashihara, Tsuyoshi Furushima, Yoshiho Ikeuchi, Yoshiho Ikeuchi, Yoshiho Ikeuchi, Yoshiho Ikeuchi   +17 more
doaj   +1 more source

Disruption of Lactate Metabolism in the Peripheral Nervous System Leads to Motor-Selective Deficits. [PDF]

Glia
Bloom AJ, Tendulkar S, Hackett AR, Strickland A, Sato-Yamada Y, Yuan L, Dong W, Ippolito J, Schmidt RE, Sasaki Y, DiAntonio A, Milbrandt J.   +11 more
europepmc   +1 more source

White matter fiber bundles enable robust conduction and time-critical signaling despite axon caliber variation. [PDF]

Commun Biol
Mordhorst L, Weiskopf N, Morawski M, Mohammadi S.   +3 more
europepmc   +1 more source

The Maintenance of Dysmyelinated Small-Diameter Axons by 14-3-3s in the Central Nervous System. [PDF]

Glia
Yamada N, Saito H, Takahashi R, Fujisato M, Hosoda Y, Sasaki B, Yamada M, Abe S, Hayashi C, Yoshimoto A, Ohkawa R, Matt TJ, M Bareyre F, Berghoff S, Simons M, Suzuki N.   +15 more
europepmc   +1 more source