Results 1 to 10 of about 308,764 (199)

Predicting the distribution of serotonergic axons: a supercomputing simulation of reflected fractional Brownian motion in a 3D-mouse brain model

Frontiers in Computational Neuroscience, 2023
The self-organization of the brain matrix of serotonergic axons (fibers) remains an unsolved problem in neuroscience. The regional densities of this matrix have major implications for neuroplasticity, tissue regeneration, and the understanding of mental ...
Skirmantas Janušonis, Justin H. Haiman, Ralf Metzler, Ralf Metzler, Thomas Vojta   +4 more
doaj   +1 more source

Multiple Copies of microRNA Binding Sites in Long 3′UTR Variants Regulate Axonal Translation

Cells, 2023
Rapid responses to changes within subcellular compartments of highly polarized cells, such as neuron axons, depend on local translation and post-transcriptional regulation.
Luba Farberov, Ariel Ionescu, Yazeed Zoabi, Guy Shapira, Amjd Ibraheem, Yosi Azan, Eran Perlson, Noam Shomron   +7 more
doaj   +1 more source

Probing brain tissue microstructure with MRI: principles, challenges, and the role of multidimensional diffusion-relaxation encoding

NeuroImage, 2023
Diffusion MRI uses the random displacement of water molecules to sensitize the signal to brain microstructure and to properties such as the density and shape of cells. Microstructure modeling techniques aim to estimate these properties from acquired data
Björn Lampinen, Filip Szczepankiewicz, Jimmy Lätt, Linda Knutsson, Johan Mårtensson, Isabella M. Björkman-Burtscher, Danielle van Westen, Pia C. Sundgren, Freddy Ståhlberg, Markus Nilsson   +9 more
doaj   +1 more source

Collagen‐rich deposit formation in the sciatic nerve after injury and surgical repair: A study of collagen‐producing cells in a rabbit model

Brain and Behavior, 2020
Introduction Posttraumatic scarring of peripheral nerves produces unwanted adhesions that block axonal growth. In the context of surgical nerve repair, the organization of the scar tissue adjacent to conduits used to span the gap between the stumps of ...
Jolanta Fertala, Michael Rivlin, Mark L. Wang, Pedro K. Beredjiklian, Andrzej Steplewski, Andrzej Fertala   +5 more
doaj   +1 more source

Pseudorabies Virus Mutants Lacking US9 Are Defective in Cytoplasmic Assembly and Sorting of Virus Particles into Axons and Not in Axonal Transport

Viruses, 2023
Herpes simplex virus (HSV) and varicella zoster virus (VZV) rely on transport of virus particles in neuronal axons to spread from sites of viral latency in sensory ganglia to peripheral tissues then on to other hosts.
Steven Adamou, Adam Vanarsdall, David C. Johnson   +2 more
doaj   +1 more source

Ontogenetic Shifts in the Number of Axons in the Olfactory Tract and Optic Nerve in Two Species of Deep-Sea Grenadier Fish (Gadiformes: Macrouridae: Coryphaenoides)

Frontiers in Ecology and Evolution, 2018
Neuroanatomical studies of the peripheral sense organs and brains of deep-sea fishes are particularly useful for predicting their sensory capabilities and ultimately their behavior.
Thomas J. Lisney, Thomas J. Lisney, Hans-Joachim Wagner, Shaun P. Collin, Shaun P. Collin   +4 more
doaj   +1 more source

Decellularized skeletal muscles display neurotrophic effects in three‐dimensional organotypic cultures

Stem Cells Translational Medicine, 2020
Skeletal muscle decellularization allows the generation of natural scaffolds that retain the extracellular matrix (ECM) mechanical integrity, biological activity, and three‐dimensional (3D) architecture of the native tissue. Recent reports showed that in
Paolo Raffa, Valentina Scattolini, Mattia Francesco Maria Gerli, Silvia Perin, Meihua Cui, Paolo De Coppi, Nicola Elvassore, Paola Caccin, Camilla Luni, Anna Urciuolo   +9 more
doaj   +1 more source

Molecular mechanisms separating two axonal pathways during embryonic development of the avian optic tectum [PDF]

, 1991
During embryonic development of the avian optic tectum, retinal and tectobulbar axons form an orthogonal array of nerve processes. Growing axons of both tracts are transiently very closely apposed to each other. Despite this spatial proximity, axons from
Adler, Alvarado-Mallart, Bixby, Bixby, Bonhoeffer, Bonhoeffer, Boxberg, Bray, Cohen, Edelman, Elsdale, Goldberg, Goldberg, Halfter, Halfter, Halfter, Halfter, Halfter, Halfter, Halfter, Hamburger, Hankin, Harris, Haydon, Kapfhammer, Kapfhammer, Kapfhammer, Katz, Kroger, Kröger, Lagenaur, LaVail, Letourneau, Letourneau, Liesi, Linser, Mattson, McCobb, McLoon, O'Leary, Puelles, Rager, Raper, Rathjen, Rogers, Rosner, Sanes, Silver, Silver, Smalheiser, Thanos, Tomaselli, Vanselow, Walter, Wictorin, Zipser   +55 more
core   +1 more source

Interplay between kinesin-1 and cortical dynein during axonal outgrowth and microtubule organization in Drosophila neurons

eLife, 2015
In this study, we investigated how microtubule motors organize microtubules in Drosophila neurons. We showed that, during the initial stages of axon outgrowth, microtubules display mixed polarity and minus-end-out microtubules push the tip of the axon ...
Urko del Castillo, Michael Winding, Wen Lu, Vladimir I Gelfand   +3 more
doaj   +1 more source

Origins of Neural Progenitor Cell-Derived Axons Projecting Caudally after Spinal Cord Injury. [PDF]

, 2019
Neural progenitor cells (NPCs) transplanted into sites of spinal cord injury (SCI) extend large numbers of axons into the caudal host spinal cord. We determined the precise locations of neurons in the graft that extend axons into the caudal host spinal ...
Anil, Selin, Dobkins, Gabriel, Ferguson, Adam R, Gomes-Leal, Walace, Graham, Lori, Huie, J Russell, Lu, Paul, Tuszynski, Mark   +7 more
core   +1 more source