Results 11 to 20 of about 210,849 (318)
Axons are generally considered as reliable transmission cables in which stable propagation occurs once an action potential is generated. Axon dysfunction occupies a central position in many inherited and acquired neurological disorders that affect both peripheral and central neurons.
Debanne, Dominique +4 more
openaire +3 more sources
Conduction in segmentally demyelinated mammalian central axons. [PDF]
The prominent symptoms associated with central demyelinating diseases such as multiple sclerosis (MS) are primarily caused by conduction deficits in affected axons.
Paul A. Felts +8 more
core +1 more source
Mistargeted axons are selectively retracted. [PDF]
zCrest:GFP labels axons that project only to the abductor muscle prior to axon injury, whereas Tubb:dsRed labels all axons. The timelapse begins at 10 hpt with 15-min intervals. In the first part, axon growth onto the adductor muscle is shown.
Koichi Kawakami (128958) +3 more
core +3 more sources
Axonal transport during injury on a theoretical axon
Neurodevelopment, plasticity, and cognition are integral with functional directional transport in neuronal axons that occurs along a unique network of discontinuous polar microtubule (MT) bundles. Axonopathies are caused by brain trauma and genetic diseases that perturb or disrupt the axon MT infrastructure and, with it, the dynamic interplay of motor ...
Soumyadeep Chandra +6 more
openaire +3 more sources
The effects of hyperglycaemic hypoxia on rectification in rat dorsal root axons [PDF]
1. Electrotonic responses to 150 ms current pulses were recorded from isolated rat dorsal roots incubated for at least 3 h with either normal (5 mM) or high (25 mM) D-glucose solutions, and with either normal (25 mM) or low (5 mM) bicarbonate ...
U Schneider +5 more
core +1 more source
Human umbilical cord mesenchymal stem cells promote peripheral nerve repair via paracrine mechanisms
Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) represent a promising young-state stem cell source for cell-based therapy. hUCMSC transplantation into the transected sciatic nerve promotes axonal regeneration and functional recovery.
Zhi-yuan Guo +4 more
doaj +1 more source
Diffusion MRI uses the random displacement of water molecules to sensitize the signal to brain microstructure and to properties such as the density and shape of cells. Microstructure modeling techniques aim to estimate these properties from acquired data
Björn Lampinen +9 more
doaj +1 more source
Axon and Myelin Morphology in Animal and Human Spinal Cord
Characterizing precisely the microstructure of axons, their density, size and myelination is of interest for the neuroscientific community, for example to help maximize the outcome of studies on white matter (WM) pathologies of the spinal cord (SC).
Ariane Saliani +7 more
doaj +1 more source
GABA increases electrical excitability in a subset of human unmyelinated peripheral axons [PDF]
A proportion of small diameter primary sensory neurones innervating human skin are chemosensitive. They respond in a receptor dependent manner to chemical mediators of inflammation as well as naturally occurring algogens, thermogens and pruritogens.
Sittl Ruth +11 more
core +1 more source

