Results 21 to 30 of about 308,764 (199)

Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoids

open access: yeseLife, 2021
During brain development, axons must extend over great distances in a relatively short amount of time. How the subcellular architecture of the growing axon sustains the requirements for such rapid build-up of cellular constituents has remained elusive ...
Patrick C Hoffmann   +6 more
doaj   +1 more source

A chloride channel in rat and human axons [PDF]

open access: yes, 1991
Current recordings from single chloride channels were obtained from excised and cell-attached patches of rat and human axons. In rat axons the channels showed an outwardly rectifying current-voltage relationship with a slope conductance of 33 pS at ...
Baker   +19 more
core   +1 more source

Neuron Names: A Gene- and Property-Based Name Format, With Special Reference to Cortical Neurons

open access: yesFrontiers in Neuroanatomy, 2019
Precision in neuron names is increasingly needed. We are entering a new era in which classical anatomical criteria are only the beginning toward defining the identity of a neuron as carried in its name.
Gordon M. Shepherd   +14 more
doaj   +1 more source

Lmx1b is required at multiple stages to build expansive serotonergic axon architectures

open access: yeseLife, 2019
Formation of long-range axons occurs over multiple stages of morphological maturation. However, the intrinsic transcriptional mechanisms that temporally control different stages of axon projection development are unknown. Here, we addressed this question
Lauren J Donovan   +7 more
doaj   +1 more source

The Flow of Axonal Information Among Hippocampal Subregions: 1. Feed-Forward and Feedback Network Spatial Dynamics Underpinning Emergent Information Processing

open access: yesFrontiers in Neural Circuits, 2021
The tri-synaptic pathway in the mammalian hippocampus enables cognitive learning and memory. Despite decades of reports on anatomy and physiology, the functional architecture of the hippocampal network remains poorly understood in terms of the dynamics ...
Yash S. Vakilna   +4 more
doaj   +1 more source

Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking

open access: yeseLife, 2016
The mechanisms regulating synapse numbers during development and ageing are essential for normal brain function and closely linked to brain disorders including dementias. Using Drosophila, we demonstrate roles of the microtubule-associated protein Tau in
Andre Voelzmann   +6 more
doaj   +1 more source

The avian tectobulbar tract: development, explant culture, and effects of antibodies on the pattern of neurite outgrowth [PDF]

open access: yes, 1990
The tectobulbar tract is the first long-distance projecting fiber pathway to appear during the development of the avian optic tectum (dorsal half of the mesencephalon).
Kröger, Stephan, Schwarz, U.
core   +2 more sources

Local Accumulation of Axonal Mitochondria in the Optic Nerve Glial Lamina Precedes Myelination

open access: yesFrontiers in Neuroanatomy, 2021
Mitochondria are essential for neurons and must be optimally distributed along their axon to fulfill local functions. A high density of mitochondria has been observed in retinal ganglion cell (RGC) axons of an unmyelinated region of the optic nerve ...
Samantha J. Wilkison   +10 more
doaj   +1 more source

Nondirected axonal growth on basal lamina from avian embryonic neural retina [PDF]

open access: yes, 1987
The vitreous surface of the embryonic avian retinal neuroepithelium was isolated by mechanical disruption of the retina mounted between 2 adhesive substrata.
Halfter, W.   +2 more
core   +1 more source

Polychlorinated Biphenyls (PCBs): Risk Factors for Autism Spectrum Disorder?

open access: yesToxics, 2020
Autism spectrum disorder (ASD) includes a group of multifactorial neurodevelopmental disorders defined clinically by core deficits in social reciprocity and communication, restrictive interests and repetitive behaviors.
Harmanpreet Kaur Panesar   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy