Neuronal Dynamics and Axonal Flow: Axonal Peristalsis [PDF]
By time-lapse, phase-contrast cinemicrography of sensory nerve fibers of young mice, isolated with their originating spinal ganglia in nutrient solution, the postulated peristaltic surface drive of the cellulifugal propulsion of the semisolid axonal column at a rate of the order of 1 mm/day (1 μm/min) could be verified and quantitatively analyzed.
openaire +2 more sources
Human umbilical cord mesenchymal stem cells promote peripheral nerve repair via paracrine mechanisms
Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) represent a promising young-state stem cell source for cell-based therapy. hUCMSC transplantation into the transected sciatic nerve promotes axonal regeneration and functional recovery.
Zhi-yuan Guo +4 more
doaj +1 more source
Axon and Myelin Morphology in Animal and Human Spinal Cord
Characterizing precisely the microstructure of axons, their density, size and myelination is of interest for the neuroscientific community, for example to help maximize the outcome of studies on white matter (WM) pathologies of the spinal cord (SC).
Ariane Saliani +7 more
doaj +1 more source
Redundancy and compensation in axon guidance: genetic analysis of the Drosophila Ptp10D/Ptp4E receptor tyrosine phosphatase subfamily [PDF]
Background: Drosophila has six receptor protein tyrosine phosphatases (RPTPs), five of which are expressed primarily in neurons. Mutations in all five affect axon guidance, either alone or in combination.
Bahri, Sami +3 more
core +4 more sources
Visualisation of ribosomes in Drosophila axons using Ribo-BiFC
The distribution of assembled, and potentially translating, ribosomes within cells can be visualised in Drosophila by using Bimolecular Fluorescence Complementation (BiFC) to monitor the interaction between tagged pairs of 40S and 60S ribosomal proteins (
Anand K. Singh +4 more
doaj +1 more source
Distinctive Structural and Molecular Features of Myelinated Inhibitory Axons in Human Neocortex. [PDF]
Numerous types of inhibitory neurons sculpt the performance of human neocortical circuits, with each type exhibiting a constellation of subcellular phenotypic features in support of its specialized functions.
Chang, Edward F +9 more
core +1 more source
AxonDeepSeg: automatic axon and myelin segmentation from microscopy data using convolutional neural networks [PDF]
Segmentation of axon and myelin from microscopy images of the nervous system provides useful quantitative information about the tissue microstructure, such as axon density and myelin thickness. This could be used for instance to document cell morphometry
Antonsanti, Pierre-Louis +5 more
core +3 more sources
This study characterizes a fluorescent Slc17a6‐tdTomato neuronal reporter mouse line with strong labeling of axons throughout the optic nerve, of retinal ganglion cell (RGC) soma in the ganglion cell layer (GCL), and of RGC dendrites in the inner ...
Puttipong Sripinun +8 more
doaj +1 more source
The Drosophila immunoglobulin gene turtle encodes guidance molecules involved in axon pathfinding [PDF]
Background: Neuronal growth cones follow specific pathways over long distances in order to reach their appropriate targets. Research over the past 15 years has yielded a large body of information concerning the molecules that regulate this process.
Al-Anzi, Bader, Wyman, Robert J.
core +4 more sources
Resveratrol promotes axonal regeneration via PI3K/Akt pathway in rats after intracerebral hemorrhage
Objective To investigate the mechanism by which resveratrol (RES) promotes axonal regeneration in rats after intracerebral hemorrhage (ICH) and explore the role of the PI3K/Akt pathway that regulates the AMPKα pathway.
WANG Guanyu +4 more
doaj +1 more source

