Results 31 to 40 of about 210,849 (318)

Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex

eLife, 2019
Cortical collapse factors affect microtubule (MT) dynamics at the plasma membrane. They play important roles in neurons, as suggested by inhibition of axon growth and regeneration through the ARF activator Efa6 in C.
Yue Qu, Ines Hahn, Meredith Lees, Jill Parkin, André Voelzmann, Karel Dorey, Alex Rathbone, Claire T Friel, Victoria J Allan, Pilar Okenve-Ramos, Natalia Sanchez-Soriano, Andreas Prokop   +11 more
doaj   +1 more source

Nondirected axonal growth on basal lamina from avian embryonic neural retina [PDF]

, 1987
The vitreous surface of the embryonic avian retinal neuroepithelium was isolated by mechanical disruption of the retina mounted between 2 adhesive substrata.
Kröger, Stephan, Kröger, S. ; https://orcid.org/, Reckhaus, W., W Halfter, W Reckhaus, S Kroger, Halfter, W.   +6 more
core   +1 more source

Ontogenetic Shifts in the Number of Axons in the Olfactory Tract and Optic Nerve in Two Species of Deep-Sea Grenadier Fish (Gadiformes: Macrouridae: Coryphaenoides)

Frontiers in Ecology and Evolution, 2018
Neuroanatomical studies of the peripheral sense organs and brains of deep-sea fishes are particularly useful for predicting their sensory capabilities and ultimately their behavior.
Thomas J. Lisney, Thomas J. Lisney, Hans-Joachim Wagner, Shaun P. Collin, Shaun P. Collin   +4 more
doaj   +1 more source

Decellularized skeletal muscles display neurotrophic effects in three‐dimensional organotypic cultures

Stem Cells Translational Medicine, 2020
Skeletal muscle decellularization allows the generation of natural scaffolds that retain the extracellular matrix (ECM) mechanical integrity, biological activity, and three‐dimensional (3D) architecture of the native tissue. Recent reports showed that in
Paolo Raffa, Valentina Scattolini, Mattia Francesco Maria Gerli, Silvia Perin, Meihua Cui, Paolo De Coppi, Nicola Elvassore, Paola Caccin, Camilla Luni, Anna Urciuolo   +9 more
doaj   +1 more source

The role of higher-order thalamus during learning and correct performance in goal-directed behavior

eLife, 2022
The thalamus is a gateway to the cortex. Cortical encoding of complex behavior can therefore only be understood by considering the thalamic processing of sensory and internally generated information.
Danilo La Terra, Ann-Sofie Bjerre, Marius Rosier, Rei Masuda, Tomás J Ryan, Lucy M Palmer   +5 more
doaj   +1 more source

Commissural Axon Kinetics and the Role of Netrin in Early Brain Circuitry Development [PDF]

, 2005
As neurons begin to differentiate, they send out processes called axons to initiate the formation of functional nerve connections. A specialized structure at the end of an axon called the growth cone is believed to possess the impressive navigational and
Bak-Maier, Magdalena
core   +1 more source

Interplay between kinesin-1 and cortical dynein during axonal outgrowth and microtubule organization in Drosophila neurons

eLife, 2015
In this study, we investigated how microtubule motors organize microtubules in Drosophila neurons. We showed that, during the initial stages of axon outgrowth, microtubules display mixed polarity and minus-end-out microtubules push the tip of the axon ...
Urko del Castillo, Michael Winding, Wen Lu, Vladimir I Gelfand   +3 more
doaj   +1 more source

Axonal Odorant Receptors Mediate Axon Targeting [PDF]

Cell Reports, 2019
In mammals, odorant receptors not only detect odors but also define the target in the olfactory bulb, where sensory neurons project to give rise to the sensory map. The odorant receptor is expressed at the cilia, where it binds odorants, and at the axon terminal.
Zamparo, Ilaria, Francia, Simona, Franchi, Sira Angela, Redolfi, Nelly, Costanzi, Elisa, Kerstens, Axelle, Fukutani, Yosuke, Battistutta, Roberto, de laureto, Patrizia Polverino, Munck, Sebastian, de Strooper, Bart, Matsunami, Hiroaki, Lodovichi, Claudia   +12 more
openaire   +4 more sources

Microglial responses around intrinsic CNS neurons are correlated with axonal regeneration [PDF]

, 2010
Background: Microglia/macrophages and lymphocytes (T-cells) accumulate around motor and primary sensory neurons that are regenerating axons but there is little or no microglial activation or T-cell accumulation around axotomised intrinsic CNS neurons ...
Bernadette ZY Wong, Shokouhi, B.N., Lieberman, A.R., Tohyama, K., Wong Bernadette ZY, Campbell, G., Koujiro Tohyama, Anderson Patrick N, Gregor Campbell, Tohyama Koujiro, Campbell Gregor, Samir Siddiqui, Siddiqui, S., Patrick N Anderson, A Robert Lieberman, Bahman N Shokouhi, Wong, B.Z.Y., Shokouhi Bahman N, Anderson, P.N., Lieberman A Robert, Siddiqui Samir   +20 more
core   +1 more source

Loss of highwire Protects Against the Deleterious Effects of Traumatic Brain Injury in Drosophila Melanogaster

Frontiers in Neurology, 2020
Traumatic brain injury is a major global cause of death and disability. Axonal injury is a major underlying mechanism of TBI and could represent a major therapeutic target.
Ciaran S. Hill, Ciaran S. Hill, Jemeen Sreedharan, Jemeen Sreedharan, Andrea Loreto, David K. Menon, David K. Menon, Michael P. Coleman, Michael P. Coleman   +8 more
doaj   +1 more source