Results 31 to 40 of about 308,764 (199)
Unrestrained growth of correctly oriented microtubules instructs axonal microtubule orientation
eLife, 2022 In many eukaryotic cells, directed molecular transport occurs along microtubules. Within neuronal axons, transport over vast distances particularly relies on uniformly oriented microtubules, whose plus-ends point towards the distal axon tip ...
Maximilian AH Jakobs +2 more
doaj +1 more source
Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury. [PDF]
, 2009 A principal objective of spinal cord injury (SCI) research is the restoration of axonal connectivity to denervated targets. We tested the hypothesis that chemotropic mechanisms would guide regenerating spinal cord axons to appropriate brainstem targets ...
Alto, Laura Taylor +5 more
core +2 more sources
A Stochastic Compartmental Model for Fast Axonal Transport [PDF]
, 2011 In this paper we develop a probabilistic micro-scale compartmental model and use it to study macro-scale properties of axonal transport, the process by which intracellular cargo is moved in the axons of neurons.
McKinley, Scott A. +2 more
core +1 more source
Toxics, 2017 PCB 11 is an emerging global pollutant that we recently showed promotes axonal and dendritic growth in primary rat neuronal cell cultures. Here, we address the influence of sex and species on neuronal responses to PCB 11.
Sunjay Sethi +2 more
doaj +1 more source
The role of higher-order thalamus during learning and correct performance in goal-directed behavior
eLife, 2022 The thalamus is a gateway to the cortex. Cortical encoding of complex behavior can therefore only be understood by considering the thalamic processing of sensory and internally generated information.
Danilo La Terra +5 more
doaj +1 more source
Large-Scale Mapping of Axonal Arbors Using High-Density Microelectrode Arrays
Frontiers in Cellular Neuroscience, 2019 Understanding the role of axons in neuronal information processing is a fundamental task in neuroscience. Over the last years, sophisticated patch-clamp investigations have provided unexpected and exciting data on axonal phenomena and functioning, but ...
Torsten Bullmann +10 more
doaj +1 more source
Why do axons differ in caliber? [PDF]
, 2012 CNS axons differ in diameter (d) by nearly 100-fold (∼0.1-10 μm); therefore, they differ in cross-sectional area (d(2)) and volume by nearly 10,000-fold.
Balasubramanian, Vijay +4 more
core +2 more sources
Frontiers in Neural Circuits, 2022 Neurons in the mouse primary visual cortex (V1) exhibit characteristic response selectivity to visual stimuli, such as orientation, direction and spatial frequency selectivity. Since V1 receives thalamic visual inputs from the lateral geniculate nucleus (
Satoru Kondo +5 more
doaj +1 more source
Uncovering Discrete Synaptic Proteomes to Understand Neurological Disorders
Proteomes, 2018 The mammalian nervous system is an immensely heterogeneous organ composed of a diverse collection of neuronal types that interconnect in complex patterns.
Yi-Zhi Wang, Jeffrey N. Savas
doaj +1 more source
Interferon inhibits the release of herpes simplex virus-1 from the axons of sensory neurons
mBio, 2023 Herpes simplex virus-1 (HSV-1) has evolved mechanisms to evade the host immune system and limit the antiviral effects induced by interferon (IFN) produced by local epithelial and immune cells.
Kevin Danastas +6 more
doaj +1 more source