Results 41 to 50 of about 199,911 (311)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Acupuncture inhibits Notch1 and Hes1 protein expression in the basal ganglia of rats with cerebral hemorrhage

Neural Regeneration Research, 2015
Notch pathway activation maintains neural stem cells in a proliferating state and increases nerve repair capacity. To date, studies have rarely focused on changes or damage to signal transduction pathways during cerebral hemorrhage. Here, we examined the
Wei Zou, Qiu-xin Chen, Xiao-wei Sun, Qing-bin Chi, Hong-yu Kuang, Xue-ping Yu, Xiao-hong Dai   +6 more
doaj   +1 more source

Spontaneous intracranial hemorrhage in infants: a clinical analysis of 131 cases

Di-san junyi daxue xuebao, 2020
Objective To explore clinical features of the etiology, imaging characteristics, complications and prognosis of spontaneous intracranial hemorrhage in infants. Methods Clinical data of 131 cases of spontaneous intracranial hemorrhage in infants (≤3 years
YANG Sha, ZHAI Xuan, LIANG Ping, ZHOU Yudong, YU Zengpeng   +4 more
doaj   +1 more source

Association of antithrombotic therapy with postoperative rebleeding in patients with cerebral amyloid angiopathy

Chinese Neurosurgical Journal, 2023
Background Cerebral amyloid angiopathy is a common cause of subcortical hemorrhage in older adults. Although open hematoma removal may be performed for severe subcortical hemorrhage, its safety in patients with cerebral amyloid angiopathy has not been ...
Taro Yanagawa, Hiroki Sato, Kaima Suzuki, Hidetoshi Ooigawa, Masaki Takao, Hiroki Kurita   +5 more
doaj   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Obesity and the risk of intracerebral hemorrhage: the multicenter study on cerebral hemorrhage in Italy.

, 2013
BACKGROUND AND PURPOSE: The effect of obesity on the risk of intracerebral hemorrhage (ICH) may depend on the pathophysiology of vessel damage. To further address this issue, we investigated and quantified the correlations between obesity and obesity-
Poli, L, Ciccone, A, Volonghi I, CASO, Valeria, Caso, V, Grassi M, Giossi A, IACOVIELLO, LICIA, Pezzini A, GRASSI, MARIO, Agnelli G, Di Castelnuovo A, PEZZINI, Alessandro, NICHELLI, Paolo Frigio, Zini, A, Lanari, A, Simone AM, LANARI, Alessia, Gamba, M, Guido, D, ZINI, Andrea, Falzone F, Nichelli, Pf, Pentore R, Padovani A, on behalf of the Multicentre Study on Cerebral Hemorrhage in Italy Investigators, Nichelli PF, Iacoviello L, Agnelli, G, Colombi M, Volonghi, I, Ritelli, M, PACIARONI, Maurizio, Silvestrelli, G, PADOVANI, Alessandro, Costa, P, De Gaetano, G, AGNELLI, Giancarlo, Gamba M, Iacoviello, L, Del Zotto, E, Grassi, M, Ritelli M, Poli L, Del Zotto E, Paciaroni M, Multicentre Study on Cerebral Hemorrhage in Italy Investigators, Morotti, A, Simone, Am, Di Castelnuovo, A, Zini A, Padovani A., COLOMBI, Marina, Morotti A, Ciccone A, Pentore, R, Silvestrelli G, Caso V, Costa P, Guido D, Paciaroni, M, SILVESTRELLI, Giorgio, Falzone, F, De Gaetano G, Lanari A, Giossi, A   +65 more
core   +1 more source

Cerebral artery dilatation maintains cerebral oxygenation at extreme altitude and in acute hypoxia : an ultrasound and MRI study [PDF]

, 2011
Transcranial Doppler is a widely used noninvasive technique for assessing cerebral artery blood flow. All previous high altitude studies assessing cerebral blood flow (CBF) in the field that have used Doppler to measure arterial blood velocity have ...
Hirani, Shashivadan P., Golay, Xavier, Imray, C. (Chris), Mark EG Edsell, Strycharczuk, L, Hugh E Montgomery, Mike PW Grocott, Imray, Christopher H. E., Wilson, M. H., Shashivadan P Hirani, Wilson, Mark H., Newman, SP, Montgomery, Hugh E., Edsell, MEG, Lisa Strycharczuk, Grocott, Mike P.W., Stanton P Newman, Mark H Wilson, Davagnanam, Indran, Caudwell Xtreme Everest Research Group, Levett, Denny Z.H., Imray, C. H. E., Edsell, M. E. G., Christopher HE Imray, Strycharczuk, Lisa, Grocott, Michael P. W., Levett, Denny Z. H., null null, Montgomery, H. E., Indran Davagnanam, John S Thornton, Grocott, M. P. W., Strycharczuk, L., Hirani, S. P., Grocott, MPW, Denny ZH Levett, Grocott, Mike P. W., Edsell, Mark E.G., Newman, S. P., Hirani, SP, Imray, Christopher H.E., Levett, D. Z. H., Wilson, MH, Xavier Golay, Newman, S. P. (Stanton P.), Davagnanam, I., Golay, X., Golay, X, Martin, D. S., Imray, CHE, Edsell, Mark E. G., Davagnanam, I, Montgomery, HE, Martin, DS, Thornton, J. S., Martin, Dan S., Thornton, John S., Levett, DZH, Dan S Martin, Thornton, JS, HASH(0x55a680246940), Newman, Stanton P.   +61 more
core   +1 more source

Research progress on high-concentration oxygen therapy after cerebral hemorrhage

Frontiers in Neurology
Recently, the role of high-concentration oxygen therapy in cerebral hemorrhage has been extensively discussed. This review describes the research progress in high-concentration oxygen therapy after cerebral hemorrhage.
He Zeng, He Zeng, Dakai Zeng, Xiaoping Yin, Xiaoping Yin, Wumiao Zhang, Wumiao Zhang, Moxin Wu, Zhiying Chen, Zhiying Chen   +9 more
doaj   +1 more source

Hypertension-Related Cerebral Microbleeds

Case Reports in Neurology, 2020
Hypertension and cerebral amyloid angiopathy are the most common causes of cerebral microbleeds. The pattern of microbleeds on T2*-weighted gradient echo sequence of magnetic resonance imaging of the brain can be indicative of the etiology of ...
Sujan T. Reddy, Sean I. Savitz
doaj   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht, Lukas Meyer, Gabriel Broocks, Matthias Bechstein, Christian Thaler, Christian Heitkamp, Laurens Winkelmeier, Vincent Geest, Alexander Heitkamp, Maximilian Jungnitz, Gregor Peter, Luca Meucci, Tobias Faizy, Jawed Nawabi, Caspar Brekenfeld, Fabian Flottmann, Maximilian Schell, Alexandros Hadjilaou, Uta Hanning, Götz Thomalla, Jens Fiehler, Susanne Gellißen, Helge C. Kniep, for the German Stroke Registry Endovascular Treatment, (GSR‐ET) Alexander Nave, Anna Alegiani, Annerose Mengel, Arno Reich, Bernd Eckert, Charlotte Pietrock, Christian Nolte, Eberhard Siebert, Fabian Flottmann, Fee Keil, Franziska Dorn, Gabor Petzold, Götz Thomalla, Hanna Zimmermann, Jan Borggrefe, Jan Hendrik Schäfer, Jens Fiehler, Joachim Röther, Klaus Gröschel, Lars Kellert, Mario Abruscato, Maximilian Schell, Omid Nikoubashman, Peter Schellinger, Silke Wunderlich, Steffen Tiedt, Sven Thonke, Timo Uphaus, Tobias Boeckh‐Behrens, Ulrike Ernemann   +53 more
wiley   +1 more source