Results 41 to 50 of about 735,797 (263)

Metabolic vulnerability index and Life’s Essential 8 with risk of major adverse cardiovascular events

npj Cardiovascular Health
The metabolic vulnerability index (MVX) captures metabolic-inflammatory vulnerability, but its joint relevance with Life’s Essential 8 (LE8) for major adverse cardiovascular events (MACE) is unclear.
Xiaojie Wang, Yanhui Gao, Gregory Y. H. Lip, Jianwen Guo, Junguo Zhang   +4 more
doaj   +1 more source

Hypertension-Related Cerebral Microbleeds

Case Reports in Neurology, 2020
Hypertension and cerebral amyloid angiopathy are the most common causes of cerebral microbleeds. The pattern of microbleeds on T2*-weighted gradient echo sequence of magnetic resonance imaging of the brain can be indicative of the etiology of ...
Sujan T. Reddy, Sean I. Savitz
doaj   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

Plant-derived nanovesicles: the intelligent nanoplatforms for therapeutics and drug delivery

Journal of Nanobiotechnology
Extracellular vesicles (EVs) are cell-secreted phospholipid bilayer vesicles that play a key role in intercellular communication by transporting molecular cargo and engaging in surface-level signaling.
Shuang Du, Dan Jia, Guohui Liang, Yonghui Dou   +3 more
doaj   +1 more source

Acupuncture inhibits Notch1 and Hes1 protein expression in the basal ganglia of rats with cerebral hemorrhage

Neural Regeneration Research, 2015
Notch pathway activation maintains neural stem cells in a proliferating state and increases nerve repair capacity. To date, studies have rarely focused on changes or damage to signal transduction pathways during cerebral hemorrhage. Here, we examined the
Wei Zou, Qiu-xin Chen, Xiao-wei Sun, Qing-bin Chi, Hong-yu Kuang, Xue-ping Yu, Xiao-hong Dai   +6 more
doaj   +1 more source

Spontaneous intracranial hemorrhage in infants: a clinical analysis of 131 cases

Di-san junyi daxue xuebao, 2020
Objective To explore clinical features of the etiology, imaging characteristics, complications and prognosis of spontaneous intracranial hemorrhage in infants. Methods Clinical data of 131 cases of spontaneous intracranial hemorrhage in infants (≤3 years
YANG Sha, ZHAI Xuan, LIANG Ping, ZHOU Yudong, YU Zengpeng   +4 more
doaj   +1 more source

Crevel H. Prediction of delayed cerebral ischemia, rebleeding, and outcome after aneurysmal subarachnoid hemorrhage. Stroke

, 1988
subarachnoid hemorrhage.
M Vermeulen, A Hijdra, H Van Crevel, Subarachnoid Hemorrhage, J Van Gijn, N J Nagelkerke   +5 more
core   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Association of antithrombotic therapy with postoperative rebleeding in patients with cerebral amyloid angiopathy

Chinese Neurosurgical Journal, 2023
Background Cerebral amyloid angiopathy is a common cause of subcortical hemorrhage in older adults. Although open hematoma removal may be performed for severe subcortical hemorrhage, its safety in patients with cerebral amyloid angiopathy has not been ...
Taro Yanagawa, Hiroki Sato, Kaima Suzuki, Hidetoshi Ooigawa, Masaki Takao, Hiroki Kurita   +5 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source